Apr 15, 2020

Elemental analysis of Moringa oleifera seeds by Laser Induced Breakdown Spectroscopy (LIBS) and its anti-cancer and anti-microbial studies

BioRxiv : the Preprint Server for Biology
Mohammed A Gondal

Abstract

Moringa oleifera plant contains a numerous antioxidants, antibiotics and nutrients (vitamins and minerals) which makes it prospective for diverse biomedical applications. This report investigated the anti-cancerous and anti-microbial potential of the Moringa oleifera seeds (MOSs) due to the bioactive components a detail elemental analysis. MOSs in the form of pellets were used in elemental analysis. Alcoholic extraction of were utilized in anti-cancerous and anti-microbial activity.To clarify the anti-cancerous and anti-microbial potential of the (MOSs) because of the bioactive components. An elemental analysis was conducted using Laser Induced Breakdown Spectroscopy (LIBS) . The GC-MS used for the validation of the LIBS outcome. Additionally, the anti-cancerous and anti-microbial activity of the MOSs was evaluated. Herein, the human colorectal carcinoma cells (HCT-116) were treated with the seeds aqueous extracts for 48 h and the cell viability plus the DNA nuclear morphology were measured via the MTT assay and DAPI staining. The cell viability of the normal human embryonic stem cells (HEK-293) was also examined after the treatment. Percentage of cell viability and inhibitory concentration (IC 50 ) of both normal and treated c...Continue Reading

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