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Engineering a circular riboregulator in Escherichia coli

bioRxiv

Sep 25, 2014

William RostainAlfonso Jaramillo

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Abstract

Circular RNAs have recently been shown to be important gene expression regulators in mammalian cells. However, their role in prokaryotes remains elusive. Here, we engineered a synthetic riboregulator that self-splice to produce a circular molecule, exploiting group I permuted intron-exo...read more

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  • Engineering a circular riboregulator in Escherichia coli

    bioRxiv

    Sep 25, 2014

    William RostainAlfonso Jaramillo

    PMID: 990008987

    DOI: 10.1101/008987

    Abstract

    Circular RNAs have recently been shown to be important gene expression regulators in mammalian cells. However, their role in prokaryotes remains elusive. Here, we engineered a synthetic riboregulator that self-splice to produce a circular molecule, exploiting group I permuted intron-exo...read more

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