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Engineering a Functional Small RNA Negative Autoregulation Network with Model-Guided Design

ACS Synthetic Biology

May 8, 2018

Chelsea Y HuJulius B Lucks

Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

Mentioned in this Paper

Gene Expression Regulation, Bacterial
Small Nuclear RNA
Solocyte
Alkalescens-Dispar Group
Testolactone
Transcription, Genetic
Protein Biosynthesis
Gene Expression
Synthetic Genes
Protein Domain
7
40
Paper Details
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Engineering a Functional Small RNA Negative Autoregulation Network with Model-Guided Design

ACS Synthetic Biology

May 8, 2018

Chelsea Y HuJulius B Lucks

PMID: 29733627

DOI: 10.1021/acssynbio.7b00440

Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

Mentioned in this Paper

Gene Expression Regulation, Bacterial
Small Nuclear RNA
Solocyte
Alkalescens-Dispar Group
Testolactone
Transcription, Genetic
Protein Biosynthesis
Gene Expression
Synthetic Genes
Protein Domain
7
40

Similar Papers Found In These Feeds

Gene Regulatory Networks

Gene regulatory networks are comprised of molecular regulators that interact with each other and other factors in a cell to regulate and modulate gene expression. Here is the latest research.

Gene Regulatory Networks (Keystone)

Gene regulatory networks are comprised of molecular regulators that interact with each other and other factors in a cell to regulate and modulate gene expression. Here is the latest research.

Related Papers

ACS Synthetic Biology

Generating Effective Models and Parameters for RNA Genetic Circuits

ACS Synthetic BiologyJune 6, 2015
Chelsea Y HuJulius B Lucks
Methods : a Companion to Methods in Enzymology

Characterizing and prototyping genetic networks with cell-free transcription-translation reactions

Methods : a Companion to Methods in EnzymologyMay 30, 2015
Melissa K TakahashiJulius B Lucks
Paper Details
References
  • References
  • Citations3
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations3
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