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Engineering a Functional Small RNA Negative Autoregulation Network with Model-Guided Design

ACS Synthetic Biology

Jun 15, 2018

Chelsea Yongxi HuJulius B. Lucks

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Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

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  • Engineering a Functional Small RNA Negative Autoregulation Network with Model-Guided Design

    ACS Synthetic Biology

    Jun 15, 2018

    Chelsea Yongxi HuJulius B. Lucks

    PMID: 29733627

    DOI: 10.1021/acssynbio.7b00440

    Abstract

    RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

    6
    43

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