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Engineering a Functional small RNA Negative Autoregulation Network with Model-guided Design

bioRxiv

Dec 1, 2017

Chelsea Y HuJulius B Lucks

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Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

Mentioned in this Paper

In Vivo
Small Nuclear RNA
Solocyte
Testolactone
Transcription, Genetic
Gene Expression
Synthetic Genes
Protein Domain
Gene Regulatory Networks
Analysis
18
1
20
Paper Details
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Engineering a Functional small RNA Negative Autoregulation Network with Model-guided Design

bioRxiv

Dec 1, 2017

Chelsea Y HuJulius B Lucks

PMID: 990227637

DOI: 10.1101/227637

Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

Mentioned in this Paper

In Vivo
Small Nuclear RNA
Solocyte
Testolactone
Transcription, Genetic
Gene Expression
Synthetic Genes
Protein Domain
Gene Regulatory Networks
Analysis
18
1
20

Feeds With Similar Papers

Gene Regulatory Networks (Keystone)

Gene regulatory networks are comprised of molecular regulators that interact with each other and other factors in a cell to regulate and modulate gene expression. Here is the latest research.

Gene Regulatory Networks

Gene regulatory networks are comprised of molecular regulators that interact with each other and other factors in a cell to regulate and modulate gene expression. Here is the latest research.

Related Papers

ACS Synthetic Biology

Generating Effective Models and Parameters for RNA Genetic Circuits

ACS Synthetic BiologyJune 6, 2015
Chelsea Y HuJulius B Lucks
Paper Details
References
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
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  • quote and clock

    No citations available

    This paper may not have been cited yet.

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