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Engineering a Functional small RNA Negative Autoregulation Network with Model-guided Design

bioRxiv

Dec 1, 2017

Chelsea Yongxi HuJulius B. Lucks

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Abstract

RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

Mentioned in this Paper

Gene Expression
Soft Tissue Rheumatism
Small Nuclear RNA
Testolactone
Nurse shark antigen receptor
RNA
Research Study
Solocyte
Gene Regulatory Networks
Core
18
1
20
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  • Engineering a Functional small RNA Negative Autoregulation Network with Model-guided Design

    bioRxiv

    Dec 1, 2017

    Chelsea Yongxi HuJulius B. Lucks

    PMID: 990227637

    DOI: 10.1101/227637

    Abstract

    RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand the repertoire of synthetic gene networks built from these regulators by constructing a transcriptional negative autoregulation (NAR) network out of small RNAs (sRNAs). NAR network motifs are core m...read more

    Mentioned in this Paper

    Gene Expression
    Soft Tissue Rheumatism
    Small Nuclear RNA
    Testolactone
    Nurse shark antigen receptor
    18
    1
    20

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