Engineering design methodology for bio-mechatronic products

Biotechnology Progress
Micael DerelövC F Mandenius

Abstract

Four complex biotechnology products/product systems (a protein purification system, a bioreactor system, a surface plasmon resonance biosensor, and an enzymatic glucose analyzer) are analyzed using conceptual design principles. A design model well-known in mechanical system design, the Hubka-Eder (HE) model, is adapted to biotechnology products that exemplify combined technical systems of mechanical, electronic, and biological components, here referred to as bio-mechatronic systems. The analysis concludes that an extension of the previous HE model with a separate biological systems entity significantly contributes to facilitating the functional and systematic analyses of bio-mechatronic systems.

Citations

Mar 26, 2010·Trends in Biotechnology·Carl-Fredrik Mandenius, Mats Björkman
Mar 8, 2012·Biotechnology Journal·Carl-Fredrik Mandenius, Mats Björkman
Dec 18, 2009·Journal of Molecular Recognition : JMR·Rebecca L Rich, David G Myszka
May 10, 2017·Biofabrication·Jonas ChristofferssonCarl-Fredrik Mandenius

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