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Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals

Nucleic Acids Research

Jul 1, 2012

Lei S QiAdam Paul Arkin

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Abstract

Non-coding RNAs (ncRNAs) are versatile regulators in cellular networks. While most trans-acting ncRNAs possess well-defined mechanisms that can regulate transcription or translation, they generally lack the ability to directly sense cellular signals. In this work, we describe a set of d...read more

Mentioned in this Paper

Retinal Nonattachment, Nonsyndromic Congenital
Ligands
Protein Biosynthesis
Monospan
RNA
RNA, Small Untranslated
RNA Conformation
Signal Transduction
RNA Aptamers
Ligands Activity
3
200
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Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals

Nucleic Acids Research

Jul 1, 2012

Lei S QiAdam Paul Arkin

PMID: 22383579

DOI: 10.1093/nar/gks168

Abstract

Non-coding RNAs (ncRNAs) are versatile regulators in cellular networks. While most trans-acting ncRNAs possess well-defined mechanisms that can regulate transcription or translation, they generally lack the ability to directly sense cellular signals. In this work, we describe a set of d...read more

Mentioned in this Paper

Retinal Nonattachment, Nonsyndromic Congenital
Ligands
Protein Biosynthesis
Monospan
RNA
3
200

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