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Engineering Transcriptional Regulator Effector Specificity using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor

bioRxiv

Feb 19, 2015

Emmanuel Lorenzo Cornejo de los SantosRichard M. Murray

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Abstract

The pursuit of circuits and metabolic pathways of increasing complexity and robustness in synthetic biology will require engineering new regulatory tools. Feedback control based on relevant molecules, including toxic intermediates and environmental signals, would enable genetic circuits...read more

Mentioned in this Paper

Small Molecule
Testolactone
Mutant
Transcriptional Regulation
Gene Mutant
lignocellulose
Compound (Substance)
Transcription Repressor/Corepressor
Dual-Energy X-Ray Absorptiometry
Inhibition of Growth
5
16
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  • Engineering Transcriptional Regulator Effector Specificity using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor

    bioRxiv

    Feb 19, 2015

    Emmanuel Lorenzo Cornejo de los SantosRichard M. Murray

    PMID: 990015438

    DOI: 10.1101/015438

    Abstract

    The pursuit of circuits and metabolic pathways of increasing complexity and robustness in synthetic biology will require engineering new regulatory tools. Feedback control based on relevant molecules, including toxic intermediates and environmental signals, would enable genetic circuits...read more

    Mentioned in this Paper

    Small Molecule
    Testolactone
    Mutant
    Transcriptional Regulation
    Gene Mutant
    5
    16

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