Enhanced activity of the combination of penicillin G and gentamicin against penicillin-resistant viridans group streptococci.

Antimicrobial Agents and Chemotherapy
E CercenadoJ C Bernaldo de Quirós

Abstract

We evaluated the effects of the combination of penicillin G and gentamicin against 10 penicillin-resistant bacteremic isolates of viridans group streptococci for which the MICs of penicillin were 4 to 64 micrograms/ml. In time-kill studies, the combination resulted in more killing of eight isolates for which the MICs of penicillin were from 8 to 64 micrograms/ml than any of the antimicrobial agents tested alone. In general, clearly enhanced antimicrobial activity was observed with the combination.

References

Jun 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E PotgieterL J Chalkley
Mar 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S HandwergerV McAuliffe
Dec 1, 1983·Antimicrobial Agents and Chemotherapy·B F FarberR C Moellering
Aug 1, 1994·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H F GuiotJ M Vossen
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Jul 1, 1993·The Journal of Antimicrobial Chemotherapy·M H WilcoxR C Spencer

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Citations

May 1, 1996·Diagnostic Microbiology and Infectious Disease·D J Biedenbach, R N Jones
Mar 17, 2004·Diagnostic Microbiology and Infectious Disease·Elizabeth CerceoEbbing Lautenbach
Apr 16, 1999·International Journal of Antimicrobial Agents·E Bouza
Jul 14, 2016·MethodsX·Navid Ziaei-DarounkalaeiLotfollah Bornaei

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