Enhanced Butanol Production by Clostridium beijerinckii BA101 Grown in Semidefined P2 Medium Containing 6 Percent Maltodextrin or Glucose.

Applied and Environmental Microbiology
J FormanekH P Blaschek

Abstract

Dramatically elevated levels of butanol and acetone resulted in higher butanol and total solvent yields for hyperamylolytic Clostridium beijerinckii BA101 relative to the NCIMB 8052 parent strain grown in semidefined P2 medium containing either 6% glucose or STAR-DRI 5 maltodextrin. C. beijerinckii BA101 consistently produced on the order of 19 g of butanol per liter in 20-liter batch fermentations. This represents a greater than 100% increase in butanol concentration by the BA101 strain compared to the parent NCIMB 8052 strain. The kinetics of butanol production over time also indicate a more rapid rate of butanol production by BA101 in semidefined P2 medium containing glucose or maltodextrin. The lower levels of butyric and acetic acids produced over the course of the fermentation carried out by BA101 are consistent with an enhanced capacity for uptake and recycling of these acids. C. beijerinckii BA101 appears to more completely utilize carbohydrate compared to the 8052 strain. Carbon balance following fermentation by C. beijerinckii 8052 and BA101 indicates that sufficient carbon is available for the twofold increase in butanol concentration observed during BA101 fermentations. C. beijerinckii BA101 also has superior solven...Continue Reading

References

Aug 1, 1990·Applied and Environmental Microbiology·B A Annous, H P Blaschek
Sep 1, 1991·Applied and Environmental Microbiology·B A Annous, H P Blaschek
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Citations

Oct 27, 2001·Applied and Environmental Microbiology·J Lee, H P Blaschek
Feb 9, 2005·Microbiology·Fanqiang WangEva R Kashket
Mar 7, 2012·Applied Biochemistry and Biotechnology·Mohamad Faizal IbrahimMohd Ali Hassan
Jan 1, 2010·Annual Review of Chemical and Biomolecular Engineering·Han LiJames C Liao
Nov 28, 2012·Journal of Industrial Microbiology & Biotechnology·Shrikant A SurvaseTom Granström
Nov 16, 2004·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Thaddeus C EzejiHans P Blaschek
Jul 5, 2007·Bioprocess and Biosystems Engineering·Nasib QureshiMichael A Cotta
Sep 27, 2013·Microbiology·Walter J Sandoval-EspinolaJosé M Bruno-Bárcena
Nov 22, 2014·Journal of Industrial Microbiology & Biotechnology·Jie Sun, Hal S Alper
Jan 19, 2016·Bioprocess and Biosystems Engineering·Young Hoon OhSi Jae Park
Nov 24, 2019·Biotechnology and Applied Biochemistry·Saraswathi NarayanasamyHuang Miao
Mar 15, 2011·Applied and Environmental Microbiology·Claire R ShenJames C Liao
Apr 25, 2012·Biotechnology Letters·German JurgensTom Granström
Feb 11, 2014·World Journal of Microbiology & Biotechnology·Lan WangHongzhang Chen
Dec 20, 2013·Environmental Technology·Bettina Schiel-BengelsdorfPeter Dürre
Feb 3, 2016·FEMS Microbiology Letters·Chang-Ting Chen, James C Liao
Jan 4, 2012·Biotechnology Journal·Michael Schmidt, Dirk Weuster-Botz
Apr 1, 2014·Preparative Biochemistry & Biotechnology·Akarin BoonsombutiSujitra Wongkasemjit
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Jan 11, 2016·World Journal of Microbiology & Biotechnology·Wilfrid J Mitchell
Oct 8, 2017·Scientific Reports·W J Sandoval-EspinolaJ M Bruno-Bárcena

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