Enhanced clinical utility of the NucliSens EasyQ RSV A+B Assay for rapid detection of respiratory syncytial virus in clinical samples

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
C MooreD Westmoreland

Abstract

The aim of the present study was to compare traditional methods for the detection of respiratory syncytial virus with a newly developed commercial assay based on real-time nucleic acid sequence based amplification. Respiratory syncytial virus is a major cause of severe respiratory infection in infants and in certain groups of older children and adults. Treatment options are limited, but a rapid diagnosis improves patient management and infection control. The rapid diagnosis of respiratory syncytial virus currently relies on antigen detection assays. These tests are limited to use in certain good-quality types of samples, which are rarely obtained from adult patients. Molecular-based assays for the detection of respiratory syncytial virus are shown to be highly sensitive, specific, and more rapid than cell culture techniques. This retrospective study compared traditional laboratory techniques for the detection of respiratory syncytial virus in 508 respiratory samples collected during the winter months of 2003-2004 against the recently developed, commercially available NucliSens EasyQ Respiratory Syncytial Virus A+B assay (bioMérieux, Marcy l'Etoile, France), which is based on real-time nucleic acid sequence based amplification u...Continue Reading

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Citations

Apr 23, 2008·Current Opinion in Pulmonary Medicine·Yoshihiko Murata
Oct 16, 2008·Clinical Microbiology Reviews·James B Mahony
Dec 22, 2006·Journal of Clinical Microbiology·Jennifer S Goodrich, Melissa B Miller
Feb 8, 2008·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Dennis WatIolo Doull
Nov 6, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C BeneriS Sood
Sep 15, 2010·Journal of Intensive Care Medicine·Karen Joan VigilRoy F Chemaly
Feb 3, 2007·Expert Review of Anti-infective Therapy·Guy Vernet
Nov 16, 2010·Expert Review of Anti-infective Therapy·James B Mahony
Dec 22, 2011·Critical Reviews in Clinical Laboratory Sciences·James B MahonyMarek Smieja
Sep 11, 2020·International Journal of Microbiology·Daniel Hussien RetaFisseha Alemu Reta
Jul 17, 2007·Clinics in Geriatric Medicine·Ann R Falsey

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