PMID: 9434974Jan 22, 1998Paper

Enhanced cross-talk correction technique for simultaneous dual-isotope imaging: a TL-201/Tc-99m myocardial perfusion SPECT dog study

Medical Physics
K Knesaurek, J Machac

Abstract

A newly developed cross-talk correction method for simultaneous dual-isotope SPECT imaging was tested in a canine model. The method is based on the assumption that the transformations, which modify the primary energy window images into the scatter images as viewed in the other energy windows, are known. These transformations were found by measuring the point spread functions (PSFs) in two different energy windows for both isotopes in water. The dual-isotope correction method is described by two convolution equations which were applied in frequency space. The equations take into account the different spatial distributions of the primary and scatter cross-talk photons. The new enhancement of the method was in applying restoration filters to the resulting corrected images. Three separate studies were acquired in our dog study: two single-isotope and one dual-isotope study. The single isotope images were used as references. The contrast between the left ventricle cavity (LVC) and the myocardium was used in transaxial and short-axis slices as a parameter to evaluate results of dual-isotope correction method with restoration. The change in contrast in the dual-isotope corrected images in both energy windows, i.e., Tc-99m primary wind...Continue Reading

References

Jan 1, 1990·European Journal of Nuclear Medicine·D SandrockR D Neumann
Jan 1, 1989·Journal of the American College of Cardiology·L L JohnsonA Reiter
Jul 1, 1986·Physics in Medicine and Biology·A Klumper, A Zwijnenburg
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