Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands

Dalton Transactions : an International Journal of Inorganic Chemistry
Diana C F MonteiroCharlotte E Willans

Abstract

A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1. Bidentate ligands show enhanced cytotoxicity over monodentate and macrocyclic ligands.

References

Mar 15, 2000·Burns : Journal of the International Society for Burn Injuries·H J Klasen
Feb 6, 2004·Journal of Medicinal Chemistry·Abdulkareem MelaiyeWiley J Youngs
Oct 29, 2004·Dalton Transactions : an International Journal of Inorganic Chemistry·Murray V BakerAllan H White
Sep 9, 2008·Accounts of Chemical Research·Nicolas Marion, Steven P Nolan
Oct 16, 2008·Biotechnology Advances·Mahendra RaiAniket Gade
Jul 8, 2009·Chemical Reviews·Khadijah M HindiWiley J Youngs
Apr 15, 2002·Angewandte Chemie·Wolfgang A Herrmann
May 8, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Marie-Laure TeyssotArnaud Gautier
Dec 8, 2010·Metallomics : Integrated Biometal Science·Siddappa PatilMatthias Tacke

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Citations

Jun 7, 2013·Medicinal Research Reviews·Ling ZhangCheng-He Zhou
Apr 4, 2017·Chemical Biology & Drug Design·Siddappa A PatilRenukadevi Patil
Dec 6, 2014·Chemical Communications : Chem Comm·Michael R ChapmanCharlotte E Willans
Mar 27, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Heba A MohamedCharlotte E Willans
Aug 8, 2015·ChemMedChem·Alexander H SandtorvHans-René Bjørsvik
Dec 12, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Luciano OehningerIngo Ott
Apr 12, 2014·Chemical Society Reviews·Anant R Kapdi, Ian J S Fairlamb
Nov 14, 2012·Chemical Society Reviews·Wukun Liu, Ronald Gust
Jul 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maura PelleiCarlo Santini
Aug 29, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Audrey BeillardXavier Bantreil
Apr 25, 2013·Metallomics : Integrated Biometal Science·Christina N Banti, Sotiris K Hadjikakou
Jul 17, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Foteini AlmaliotiAthanasia Dervisi
Apr 24, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Alice JohnsonKogularamanan Suntharalingam
May 13, 2021·Drug Development Research·Serap Şahin-BölükbaşıOzan Kılıçkaya
May 22, 2021·Journal of the American Society for Mass Spectrometry·Mustafa GülfenChung-Hsuan Chen

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