Enhanced fluorescence detection of cis-combretastatins by post-column photolysis

Journal of Chromatography. a
Michael Stratford

Abstract

A method is described to enhance the sensitivity of fluorescence detection of cis-combretastatins using a short post-column photolysis coil with a mercury lamp, by inducing the rapid conversion to the trans isomer. Although all the compounds studied showed enhanced fluorescence after photolysis, there were large differences in the absolute level, with the inherent response of the catechol CA1 being much lower than the corresponding phenolic CA4. Brief exposure to the deuterium lamp in a photodiode array detector also resulted in significant enhancement.

References

Feb 23, 1999·Journal of Chromatography. B, Biomedical Sciences and Applications·M R Stratford, M F Dennis

❮ Previous
Next ❯

Citations

Jul 2, 2011·Journal of Natural Products·Rajendra P TanpureKevin G Pinney
Aug 9, 2011·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Michael R L Stratford, Lisa K Folkes
Jun 25, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Tim MeyerRichard H Begent

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Gordon J S RustinPatricia M Price
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Howard W Salmon, Dietmar W Siemann
Archives of Biochemistry and Biophysics
Lisa K FolkesPeter Wardman
© 2021 Meta ULC. All rights reserved