Enhanced Gastric Emptying Scintigraphy to Assess Fundic Accommodation Using Intragastric Meal Distribution and Antral Contractility

Journal of Nuclear Medicine Technology
Perry OrtheyA H Maurer

Abstract

Gastric emptying scintigraphy (GES) as now commonly performed measures only total gastric emptying. Intragastric meal distribution (IMD) immediately post meal ingestion (t= 0 min) (IMD0) ) can assess fundic accommodation (FA) and dynamic antral contraction scintigraphy (DACS) can assess antral motility. 1) Incorporate IMD and DACS into GES; 2) Compare IMD0 using gastric division into anatomic proximal and distal halves vs more physiologic separation of the antrum from proximal stomach using DACS; 3) establish normal values. Methods: Normal subjects (n = 20) underwent GES using a solid-liquid meal. DACS (1 frame/3 sec) was performed for 20 minutes after each static imaging time. IMD0 was measured by using both semi-automated software to divide the gastric long axis in anatomic halves and Fourier analysis to identify antral pixels with phasic contractions. Results: Using division of stomach in halves (IMD0(½) averaged 0.75±0.15 (SD). Using phasic contractions to define the antrum, mean IMD0(AC) was 0.85±0.14 (P = 0.004). Sustained antral contractions started at mean 11.24±12.98 minutes after meal ingestion and originated in gastric mid-body with starting location 40.5±10.8% from distal to proximal stomach along its long axis. Ant...Continue Reading

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Citations

Sep 30, 2019·Gut·Madhusudan GroverVincenzo Stanghellini
Jun 2, 2020·World Journal of Gastroenterology : WJG·Yu GuoJiande Dz Chen
Nov 5, 2019·American Journal of Physiology. Gastrointestinal and Liver Physiology·Perry OrtheyAlan H Maurer
Jul 29, 2020·Gastroenterology Clinics of North America·Alan H Maurer
Apr 26, 2019·Journal of Nuclear Medicine Technology·Patrick M Colletti
Aug 3, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Liz Febo-RodriguezRobert J Shulman
Dec 11, 2021·Nuclear Medicine Communications·Tzu-Wei KuanTzu Hsuan Chen

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