PMID: 4288593Nov 4, 1966Paper

Enhanced growth of human embryonic cells infected with adenovirus 12

Science
I V Sultanian, G Freeman

Abstract

Fibroblast-like cells from human embryonic lung were infected with adenovirus type 12, and they survived as an established line, with the characteristics of "transformation" following considerable cellular killing. Inclusion bodies disappeared and cells became resistant to reinfection with type 12 virus as they grew in thick multilayered strands, and giant and syncytial cells became commonplace. An induced new cell antigen demonstrable by complement-fixation and fluorescent-antibody studies persisted for at least 20 culture passages after infection.

References

Feb 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·J D LevinthalJ J Trentin
Dec 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·J L RiggsE H Lennette
Sep 14, 1962·Science·J J TRENTING TAYLOR
Aug 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·R J HUEBNERW T LANE
Oct 1, 1964·The Journal of Experimental Medicine·J H POPE, W P ROWE

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Citations

Mar 1, 1967·Postgraduate Medical Journal·H A Reimann
Jan 1, 1972·Journal of Clinical Pathology. Supplement (Royal College of Pathologists)·H G Pereira
May 30, 1967·Biochimica Et Biophysica Acta·R S Yolles, G Freeman
Sep 20, 1968·Science·G Freeman

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