Enhanced Immune Protection of Mud Crab Scylla paramamosain in Response to the Secondary Challenge by Vibrio parahaemolyticus.

Frontiers in Immunology
Xin ZhangZiping Zhang

Abstract

"Immune priming" plays a vital part in the immune system of invertebrates, protecting against recurrent infections by pathogens, and can provide some ideas for the prevention and treatment of invertebrate diseases. Many invertebrates have been demonstrated recently to have immune priming, but the relevant mechanisms are not known. Expression of immune system-related genes in the hemocytes and hepatopancreas of the mud crab (Scylla paramamosain) before and after repeated stimulation with Vibrio parahaemolyticus were analyzed by real-time fluorescence quantitative polymerase chain reaction. Some molecules that may participate in the immune priming of S. paramamosain were screened out, and their possible roles in immune priming were interpreted. Crabs injected first with heat-killed V. parahaemolyticus (HkVp group) or physiologic (0.9%) saline (PS group) were rechallenged at 168 h with live V. parahaemolyticus (HkVp+Vp group and PS+Vp group, respectively). The log-rank test shows a significant difference in survival rate between the HkVp+Vp group and the other groups after the ICH (p < 0.05). Expression of genes involved in the toll-like receptor (TLR) signaling pathway and some antimicrobial peptide genes were detected. By, respe...Continue Reading

References

Nov 1, 1976·Transplantation·R D Karp, W H Hildemann
Sep 1, 1982·European Journal of Immunology·C Langlet, J Bierne
Oct 7, 2000·Diseases of Aquatic Organisms·C A VenegasK Murog
Nov 9, 2000·Proceedings of the National Academy of Sciences of the United States of America·Z Pancer
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Sep 5, 2003·Nature·Joachim Kurtz, Karoline Franz
Dec 20, 2003·The EMBO Journal·Huaiyu SunSteven A Wasserman
Dec 15, 2004·Microbes and Infection·Joachim Kurtz
Mar 31, 2005·Trends in Immunology·Joachim Kurtz
Jun 23, 2005·Nature Immunology·Tom J LittleAndrew F Read
Aug 20, 2005·Science·Fiona L WatsonDietmar Schmucker
May 17, 2006·Trends in Ecology & Evolution·Tom J Little, Alex R Kraaijeveld
Jun 20, 2006·Current Biology : CB·Ben M Sadd, Paul Schmid-Hempel
Mar 14, 2007·PLoS Pathogens·Linh N PhamDavid S Schneider
Mar 14, 2007·Journal of Fish Diseases·S-P WengJ-G He
Sep 20, 2007·Nature Immunology·Philip D HodgkinAlan G Baxter
Sep 26, 2007·Nature Reviews. Immunology·Melvin CohnMartin Weigert
Oct 16, 2007·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Chris Hauton, Valerie J Smith
Nov 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Andrew F Rowley, Adam Powell
Mar 19, 2008·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Tom J LittlePaul Schmid-Hempel
Apr 12, 2008·Molecular Biology and Evolution·Daniela BritesLouis Du Pasquier
Apr 22, 2008·Molecular Biology Reports·Chanprapa ImjongjirakSiriporn Sittipraneed
Feb 10, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Nolwenn M DheillyDavid A Raftos
Mar 10, 2009·Fish & Shellfish Immunology·Fei ZhuZi-Rong Xu
Aug 18, 2010·Vaccine·Muriel Moser, Oberdan Leo
Nov 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Patrick C HaningtonEric S Loker
May 18, 2011·Cell Host & Microbe·Mihai G NeteaJos W M van der Meer
Sep 29, 2011·Developmental and Comparative Immunology·Zhongyang LinXiuying Wang
Jan 10, 2012·Annual Review of Immunology·Thomas BoehmMax D Cooper
Apr 17, 2012·BMC Evolutionary Biology·Sophie A O ArmitageIgnacio G Bravo
Aug 10, 2012·Biology Letters·Seanna J McTaggartTom J Little
Jan 25, 2013·Journal of Innate Immunity·Julien PortelaBenjamin Gourbal
Feb 15, 2013·PLoS Pathogens·Michael F Criscitiello, Paul de Figueiredo
May 15, 2013·Fish & Shellfish Immunology·Jingjing WangLinsheng Song
Mar 19, 2014·Current Opinion in Immunology·Jessica QuintinMihai G Netea

❮ Previous
Next ❯

Datasets Mentioned

BETA
JQ824130

Methods Mentioned

BETA
electrophoresis
PCR

Software Mentioned

String
Pelle
R Programming Language
GraphPad Prism
OmicShare
Cytoscape

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.