Enhanced marrow [18F]fluorodeoxyglucose uptake related to myeloid hyperplasia in Hodgkin's lymphoma can simulate lymphoma involvement in marrow

Clinical Lymphoma
Rebecca L ElstromStephen Schuster

Abstract

[18F]Fluorodeoxyglucose (FDG) positron emission tomography (PET) is increasingly used for the clinical staging of lymphomas and for assessment of response to therapy. We report the case of a woman with classic Hodgkin's lymphoma who had marked FDG uptake by tumor and bone marrow suggestive of diffuse marrow involvement by lymphoma. However, iliac crest bone marrow examination showed marked myeloid hyperplasia without evidence of lymphoma involvement. We discuss the implications for interpretation of FDG-PET imaging of bone marrow in lymphomas.

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Citations

Sep 1, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Toshiki KazamaHomer A Macapinlac
Oct 1, 2008·Current Hematologic Malignancy Reports·Rebecca L Elstrom, John P Leonard
Jul 25, 2009·Annals of Nuclear Medicine·Kentaro InoueHiroshi Fukuda
May 17, 2005·Radiologic Clinics of North America·Bruno C Vande BergJacques Malghem
Oct 13, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Ingeborg GoethalsHamphrey Ham
Nov 28, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Hugo J A AdamsRutger A J Nievelstein
Jun 21, 2014·AJNR. American Journal of Neuroradiology·Y ShigematsuY Yamashita
May 23, 2006·Clinical Nuclear Medicine·Avneesh ChhabraP Todd Makler
Aug 22, 2006·Clinical Nuclear Medicine·Elinor GoshenS Tzila Zwas
Oct 22, 2008·Clinical Nuclear Medicine·Henriette M E Quarles van UffordJohn M H de Klerk
Sep 22, 2007·Clinical Nuclear Medicine·Masatoyo NakajoMasayuki Nakajo
Aug 12, 2005·Current Opinion in Oncology·Guy JerusalemGeorges Fillet
Aug 10, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Michael S ClarkGeoff B Johnson
Sep 13, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Juliano J CerciRobert Carr

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