PMID: 6162079Jan 1, 1980Paper

Enhanced production of virus-inhibiting factor (interferon) in human diploid cells by ultraviolet irradiation and temperature shift-down after stimulation with Newcastle disease virus

Microbiology and Immunology
N MaeharaM Matumoto

Abstract

The production of the virus-inhibiting factor or interferon (IF) was highest in cells incubated at 37 C after inoculation with Newcastle disease (ND) virus and decreased as the incubation temperature was lowered. Shift-down of incubation temperature to 32 C or 34 C after incubation at 37 C for 4--7 hr enhanced IF production in cell cultures stimulated with ND virus, as compared with cultures incubated continuously at 37 C. Shift-down to 32 C after incubation at 37 C for 6 hr was optimal for this enhancement of IF yield. Enhanced IF production was also observed in cell cultures irradiated by ultraviolet light 4--7 hr after stimulation with ND virus.

References

Jun 1, 1978·The Journal of General Virology·K Cantell, S Hirvonen
Jan 1, 1975·Journal of Clinical Microbiology·H StranderK Cantell
Jan 1, 1978·Advances in Experimental Medicine and Biology·H L KauppinenK Cantell
Jan 1, 1978·Advances in Experimental Medicine and Biology·M D JohnstonN B Finter
Jan 1, 1978·Journal of Biological Standardization·G M ScottD Dicker
Jan 1, 1978·Advances in Experimental Medicine and Biology·J K Dunnick, G J Galasso
Jul 1, 1979·Antimicrobial Agents and Chemotherapy·A BilliauP De Somer
Jan 1, 1978·Advances in Experimental Medicine and Biology·V G EdyP DeSomer
Apr 1, 1973·The Journal of General Virology·A BilliauP De Somer
Jan 1, 1974·Japanese Journal of Microbiology·A MatsuoT Kishida
Dec 1, 1972·Antimicrobial Agents and Chemotherapy·E A Havell, J Vilcek
Jan 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·M HoJ A Armstrong
Jan 1, 1969·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J Coppey, P Markovits
Jan 1, 1966·Virology·D C Burke, J M Morrison

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.