Enhanced Recovery After Surgery for Advanced Ovarian Cancer: A Systematic Review of Interventions Trialed

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Kristina LindemannAlison Brand

Abstract

We sought to summarize the evidence for interventions aiming at enhanced recovery after surgery (ERAS) in ovarian cancer through a systematic review. We searched MEDLINE, EMBASE, and The Cochrane Library for studies testing ERAS interventions in patients undergoing surgery for ovarian cancer. Study selection and data extraction were done independently by 2 reviewers with disagreements resolved by discussion with a senior, third reviewer. We identified 25 studies including 1648 participants with ovarian cancer. Nine observational studies addressed ERAS protocols. Four of them were prospective, and 3 included historical controls. The other 16 studies reported single interventions, for example, early feeding, omission of pelvic drains, early orogastric tube removal, Doppler-guided fluid management, and patient-controlled epidural analgesia. Early feeding protocols were tested in 7 of the 12 randomized trials. Early feeding appeared to be safe and was associated with significantly faster recovery of bowel function. Few studies have specifically studied ERAS interventions in ovarian cancer. All studies on protocols including multiple interventions were susceptible to bias. Early feeding is the intervention that is best supported by ...Continue Reading

References

Dec 12, 2003·Lancet·Henrik Kehlet, Jørgen B Dahl
Apr 14, 2006·Acta Obstetricia Et Gynecologica Scandinavica·Charlotte MarxHenrik Kehlet
Jun 1, 2006·Journal of the American College of Surgeons·Kathrine Holte, Henrik Kehlet
May 6, 2008·Cancer Nursing·Suwen FengYeqing Qiu
Jun 3, 2008·American Journal of Obstetrics and Gynecology·Dana M ChaseBradley J Monk
Jul 25, 2008·Annals of Surgery·Henrik Kehlet, Douglas W Wilmore
Apr 15, 2009·Journal of Surgical Oncology·Jalid SehouliOskay-Ozcelik Gülten
May 22, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cagla EskiciogluRobin S McLeod
Feb 2, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Krishna K VaradhanDileep N Lobo
Jun 5, 2010·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Jonathan CarterChris Dalrymple
Apr 15, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P A Cascales CamposP Parrilla Paricio
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
May 24, 2012·Gynecologic Oncology·Eleftheria KalogeraWilliam A Cliby
Jun 12, 2012·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Verinder S SidhuAlison H Brand
Nov 17, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Supratik ChattopadhyayKhadra Galaal
Mar 9, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H CakirA P J Houdijk
Aug 24, 2013·Obstetrics and Gynecology·Eleftheria KalogeraSean C Dowdy
May 16, 2014·Acta Obstetricia Et Gynecologica Scandinavica·Lena WijkKerstin Nilsson
Oct 16, 2014·Gynecologic Oncology·Gregg NelsonSean C Dowdy
Nov 28, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Jeanny J A de GrootBrigitte F M Slangen

❮ Previous
Next ❯

Citations

Jan 15, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Elisa PiovanoKristina Lindemann
Apr 3, 2019·International Journal of Occupational Safety and Ergonomics : JOSE·Joseph FlanneryAdekunle S Oyegoke
Mar 6, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Reshu AgarwalUnnikrishnan U G
Oct 17, 2019·Archives of Gynecology and Obstetrics·S SchneiderJ Sehouli
Jul 17, 2019·Surgical Endoscopy·Eric LambaudieGilles Houvenaeghel
Aug 3, 2020·JAAPA : Official Journal of the American Academy of Physician Assistants·Shilpa GajarawalaMark Archambault
Dec 3, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Eric LambaudiePatricia Marino
Jan 23, 2021·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Wolfgang Schwenk
Mar 2, 2021·British Journal of Nursing : BJN·Dorthe Hjort JakobsenLene Seibæk

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.