Enhanced Social Attention in Female Infant Siblings at Risk for Autism

Journal of the American Academy of Child and Adolescent Psychiatry
Katarzyna ChawarskaFrederick Shic

Abstract

Sexual dimorphism in autism spectrum disorders (ASD) is a well-recognized but poorly understood phenomenon. Females are four times less likely to be diagnosed with ASD than males and, when diagnosed, are more likely to exhibit comorbid anxiety symptoms. One of the key phenotypic features of ASD is atypical attention to socially relevant stimuli. Eye-tracking studies indicate atypical patterns of spontaneous social orienting during the prodromal and early syndromic stages of ASD. However, there have been no studies evaluating sex differences in early social orienting and their potential contribution to later outcomes. We examined sex differences in social orienting in 6-, 9-, and 12-month-old infants at high genetic risk for ASD (n = 101) and in low-risk controls (n = 61), focusing on neurobehavioral measures of function across a spectrum of autism risk. Results suggest that, between 6 and 12 months of age, a period highly consequential for the development of nonverbal social engagement competencies, high-risk females show enhanced attention to social targets, including faces, compared to both high-risk males and low-risk males and females. Greater attention to social targets in high-risk infants was associated with less severe ...Continue Reading

References

May 23, 2002·Science·Olivier PascalisCharles A Nelson
Jul 16, 2003·Proceedings of the National Academy of Sciences of the United States of America·Patricia K KuhlHuei-Mei Liu
Aug 27, 2003·Child Development·Katarzyna ChawarskaFred Volkmar
Sep 1, 2004·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Annette Karmiloff-SmithRuth Campbell
Mar 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·O PascalisC A Nelson
Mar 31, 2005·Journal of Autism and Developmental Disorders·Annelies de BildtRuud Minderaa
Jul 27, 2007·Proceedings of the National Academy of Sciences of the United States of America·Xiaoyue ZhaoMichael Wigler
Dec 10, 2008·Biological Psychiatry·Mayada ElsabbaghMark H Johnson
Feb 18, 2010·The American Statistician·Jan SerroyenMarie Davidian
Jul 3, 2010·The American Journal of Psychiatry·Thomas InselPhilip Wang
Nov 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Martha D KaiserKevin A Pelphrey
Dec 7, 2010·Brain Research·Frederick ShicKatarzyna Chawarska
Mar 26, 2011·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Angelica Ronald, Rosa A Hoekstra
Mar 29, 2011·Journal of Autism and Developmental Disorders·Marjorie SolomonCameron S Carter
May 31, 2011·Journal of Vision·Benjamin W TatlerDana H Ballard
Sep 3, 2011·Developmental Science·Elizabeth K JohnsonAnne Cutler
Nov 19, 2011·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Peter SzatmariAnn Thompson
Jan 4, 2012·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Gaia ScerifKim Cornish
Jan 27, 2012·Journal of Autism and Developmental Disorders·Rachael BedfordUNKNOWN BASIS team
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·David J Lewkowicz, Amy M Hansen-Tift
Mar 21, 2012·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Katarzyna ChawarskaFrederick Shic
Mar 29, 2012·Journal of Autism and Developmental Disorders·Lonnie ZwaigenbaumCaroline Roncadin
Apr 17, 2012·American Journal of Human Genetics·Daisuke SatoStephen W Scherer
Jul 31, 2012·Journal of the American Academy of Child and Adolescent Psychiatry·Katharina DworzynskiFrancesca Happé
Aug 1, 2012·Behavioural Brain Research·Mayada ElsabbaghUNKNOWN BASIS Team
Feb 7, 2013·Social Cognitive and Affective Neuroscience·Mayada ElsabbaghUNKNOWN BASIS Team
Feb 15, 2013·Current Opinion in Neurology·Donna M Werling, Daniel H Geschwind
Feb 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Elise B RobinsonAngelica Ronald
Mar 5, 2013·Journal of the American Academy of Child and Adolescent Psychiatry·Daniel MessingerMarian Sigman
Jul 24, 2013·Journal of Autism and Developmental Disorders·Daniel J CampbellKatarzyna Chawarska
Aug 21, 2013·Biological Psychiatry·Frederick ShicKatarzyna Chawarska
Jan 28, 2014·Journal of Autism and Developmental Disorders·Jessica H SchroederJonathan A Weiss
Mar 4, 2014·American Journal of Human Genetics·Sébastien JacquemontEvan E Eichler
Mar 25, 2014·Journal of the American Academy of Child and Adolescent Psychiatry·Sally OzonoffAna-Maria Iosif
Dec 3, 2014·Journal of the American Academy of Child and Adolescent Psychiatry·Katarzyna ChawarskaSusan Bryson
Dec 20, 2014·Journal of the American Academy of Child and Adolescent Psychiatry·Meng-Chuan LaiSimon Baron-Cohen
Apr 30, 2015·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Sally OzonoffAna-Maria Iosif
Jun 6, 2015·Molecular Autism·Daniel S MessingerLonnie Zwaigenbaum
Oct 6, 2015·Journal of Child Language·Elena J TenenbaumJames L Morgan

❮ Previous
Next ❯

Citations

Feb 24, 2016·Journal of the American Academy of Child and Adolescent Psychiatry·Somer L BishopStephan J Sanders
Feb 18, 2016·The Quarterly Journal of Experimental Psychology : QJEP·Sara Jane WebbSusan Faja
Apr 2, 2016·Molecular Autism·Rachael BedfordTeodora Gliga
Apr 22, 2017·Autism : the International Journal of Research and Practice·Rene JamisonAlycia K Halladay
Jan 25, 2018·Annals of the New York Academy of Sciences·Devanand S Manoli, Jessica Tollkuhn
Jan 24, 2018·Autism Research : Official Journal of the International Society for Autism Research·Carolyn E B McCormickBarry L Lester
Mar 3, 2018·Journal of Autism and Developmental Disorders·Lauren P LawsonCheryl Dissanayake
Jul 26, 2018·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Martina FranchiniIsabel M Smith
Nov 24, 2018·Journal of Autism and Developmental Disorders·Johan Lundin KlebergTerje Falck-Ytter
Aug 2, 2019·Autism Research : Official Journal of the International Society for Autism Research·Juan KouKeith M Kendrick
Dec 5, 2019·Autism Research : Official Journal of the International Society for Autism Research·Clare HarropJulia Parish-Morris
Dec 5, 2019·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Tessa ClarksonMitchell J Prinstein
Jul 21, 2020·Development and Psychopathology·Gabrielle M Tiede, Katherine M Walton
Oct 4, 2020·Journal of Autism and Developmental Disorders·Serene HabayebLaura A Edwards
Apr 4, 2019·Primates; Journal of Primatology·Mathilde GramppJennifer Botting
Apr 27, 2018·Journal of Autism and Developmental Disorders·Paula Morales-HidalgoJosefa Canals
Mar 29, 2018·Journal of Autism and Developmental Disorders·Qiandong WangLi Yi
Apr 10, 2019·Molecular Autism·Jaclin BoorseJulia Parish-Morris
May 16, 2020·Journal of Autism and Developmental Disorders·Einat Waizbard-BartovDavid G Amaral
Nov 22, 2016·Journal of Neuroscience Research·Meng-Chuan LaiSimon Baron-Cohen
Jun 8, 2018·Frontiers in Psychology·Kirsten A DalrympleJed T Elison
Oct 21, 2017·Journal of Autism and Developmental Disorders·Sarah OrmondTony Attwood
Aug 1, 2020·Journal of Autism and Developmental Disorders·Amy Tanner, Katerina Dounavi
Jan 13, 2021·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Mark H JohnsonEmily J H Jones
Feb 17, 2021·Journal of Autism and Developmental Disorders·Kelly JensenUNKNOWN Autism Working Group in Peru
Aug 11, 2018·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Erin KangMatthew D Lerner
Aug 15, 2021·Infant Behavior & Development·Claire F NoonanJulie Markant
Dec 28, 2021·Autism : the International Journal of Research and Practice·Adeline LacroixMartial Mermillod

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