Enhancement of calcyclin gene RNA expression in squamous cell carcinoma of the oral mucosa, but not in benign lesions

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
G N BertaF Di Carlo

Abstract

Oral cancer is a neoplasm with some known causes. Proliferation genes are significant among its few pathogenetic and prognostic factors. Calcyclin is a cell-cycle-related gene, the function of which is still unclear. Its expression and that of Haras and histone-H3 have been investigated in an assessment of their pathogenetic role in squamous cell carcinoma. RNA extracted from the pathological and normal mucosa of patients with squamous cell carcinoma (SCC) and benign lesions was reverse transcribed and amplified by the polymerase chain reaction (PCR). The expression of all three genes in the pathological mucosa was enhanced in SCC only. This suggests that they may be involved in its pathogenesis and provides another parameter for the differentiation of malignant and benign lesions.

References

Nov 10, 1992·Biochimica Et Biophysica Acta·S W BargerL J Van Eldik
Jun 1, 1992·Current Opinion in Oncology·P BoyleC Scully
Jun 1, 1991·Journal of Surgical Oncology·R PillaiP Balaram
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A M WangD F Mark
Feb 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·J Hoellering, C F Shuler
Aug 28, 1989·FEBS Letters·J KuźnickiB Kamińska
Sep 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·S Nakajima-IijimaT Kakunaga
Apr 1, 1986·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·F MarashiJ Stein
Mar 1, 1987·Journal of Oral Pathology·J K Field, D A Spandidos
Oct 1, 1988·The British Journal of Oral & Maxillofacial Surgery·M PartridgeM Sherriff
Mar 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·B CalabrettaR Baserga
Jul 1, 1986·Postgraduate Medicine·W F McGuirt
Oct 7, 1986·Biochemistry·F Shahbakhti, W B Gratzer
Aug 24, 1995·Biochemical and Biophysical Research Communications·J J van GroningenH P Bloemers
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F X BoschA I Born
Jun 19, 1993·International Journal of Cancer. Journal International Du Cancer·D M ParkinJ Ferlay
Jul 5, 2007·Journal of Lipid Research·Barbara P AtshavesFriedhelm Schroeder

❮ Previous
Next ❯

Citations

Jun 1, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S DelorgeS Hassid
Jul 8, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J StulíkC W Heizmann
Sep 8, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A SethC P Vary
Aug 19, 2008·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Dipak SapkotaSalah O Ibrahim
Oct 26, 2012·The FEBS Journal·Leyuan BaoSreenivasan Ponnambalam
Dec 30, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Yang LiDavid T Wong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.