Enhancement of polysome formation and protein synthesis in Sendai virus-infected cells

The Journal of General Virology
V M ZaĭdesA G Bukrinskaya

Abstract

A considerable stimulation of total protein synthesis in Sendai virus-infected chicken fibroblasts occurred 18 h after infection. The stimulation of synthesis was shown to be due mainly to the synthesis of virus-specific proteins; the synthesis of host proteins was either unchanged or slightly enhanced. The level of functional polyribosomes in virus-infected cells was also increased as compared to that in mock-infected control while the number of free 80S ribosomes was proportionally decreased.

Related Concepts

Chick Embryo
Para-Influenza Virus Type 1
Peptide Biosynthesis
Polyribosomes
Protein Biosynthesis
Viral Proteins
Culture Techniques

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