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Enhancement of the antigenic activity and virulence of the vaccine strain E of Rickettsia prow azeki by passages in cell culture

Acta Virologica

Nov 1, 1975

V F Ignatovich

PMID: 1993

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Abstract

Changes in the biological properties of the vaccine strain E of Rickettsia prowazeki occurred upon cultivation of A1 (human amnion) cells infected with this strain. In the course of passages of these cells the antigenic activity and virulence of the rickettsia increased. The changes wer...read more

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Antibodies, Bacterial
Virus Replication
Metazoa
Structure of Amnion
Cavia porcellus
Pathogenicity
Antibody Formation
Rickettsia prowazekii
Rickettsial Vaccines
Chick Embryo
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  • Enhancement of the antigenic activity and virulence of the vaccine strain E of Rickettsia prow azeki by passages in cell culture

    Acta Virologica

    Nov 1, 1975

    V F Ignatovich

    PMID: 1993

    DOI:

    Abstract

    Changes in the biological properties of the vaccine strain E of Rickettsia prowazeki occurred upon cultivation of A1 (human amnion) cells infected with this strain. In the course of passages of these cells the antigenic activity and virulence of the rickettsia increased. The changes wer...read more

    Mentioned in this Paper

    Antibodies, Bacterial
    Virus Replication
    Metazoa
    Structure of Amnion
    Cavia porcellus

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