PMID: 6983744Sep 1, 1982Paper

Enhancement of the in vitro colony-forming capacity of human T lymphocytes induced by levamisole

Thymus
V PistoiaF Patrone

Abstract

The colony-forming capacity of normal peripheral blood mononuclear cells and of TG-depleted cell suspensions induced by PHA was investigated in the presence of different concentrations of levamisole. The results obtained demonstrate that: (1) the drug enhances significantly the number of colonies formed by both mononuclear cells and TG-depleted cells at concentrations ranging from 5 x 10(-6) to 5 x 10(-8 M; (2) this stimulatory activity results from a direct effect on T cells; and (3) adherent accessory cells are unaffected by the in vitro treatment with levamisole.

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.