PMID: 6104819Mar 1, 1980Paper

Enhancement of tyrosine hydroxylase activity by Oxotremorine does not affect sleep in the rat

Pharmacology, Biochemistry, and Behavior
P Ramm, H Taub

Abstract

Marked enhancement of tyrosine hydroxylase (TH) activity was observed in the rostral pons of Wistar albino rats, 3 days after a single injection of Oxotremorine. TH activity in other brain areas, and regional levels of norepinephrine, dopamine, serotonin and 5-hydroxyindoleacetic acid were unaffected. Enhancement of TH activity did not affect length or number of REM episodes, or the amount of REM occurring in 24 hr. REM occurrence did not, thus, vary in accordance with activity of the rate-limiting enzyme for catecholamine synthesis. These data suggest that, although REM may reflect neuronal protein synthesis, REM is not part of a mechanism regulating the activity of enzymes in the pontine CA synthesis pathway.

References

Jan 1, 1975·Neuroendocrinology·R R Drucker-ColínJ L McGaugh
Jul 18, 1977·Psychopharmacology·J A Rojas-RamírezR R Drucker-Colín
Jan 1, 1977·Progress in Neurobiology·D G Amaral, H M Sinnamon
Apr 1, 1979·Behavioral and Neural Biology·P Ramm
Jan 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·H ThoenenJ Axelrod
Aug 30, 1969·Nature·I Oswald
Jan 1, 1971·Psychopharmacologia·J D CoulterH L Williams
Nov 27, 1972·Brain Research·W C SternJ E Jalowiec
Jan 1, 1973·Psychopharmacologia·W C Stern, P J Morgane
Sep 1, 1973·Behavioral Biology·V PegramW Bridgers
May 1, 1968·International Journal of Neuropharmacology·R P MaickelF P Miller
Oct 1, 1967·Canadian Journal of Biochemistry·E G McGeerP L McGeer

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Citations

Jul 1, 1989·Electroencephalography and Clinical Neurophysiology·G S RuigtL A Van Wezenbeek
Jun 26, 2007·Environmental Monitoring and Assessment·Mehmet AydinVeli Uygur

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