PMID: 8593287Oct 1, 1995Paper

Enhancing effects of chicken egg white derivatives on the phagocytic response in the dog

The Journal of Veterinary Medical Science
Y HirotaT Onodera

Abstract

Immunostimulative effects of chicken egg white derivatives (EWD) on phagocytic responses of peripheral blood mononuclear cells (MNC) and polymorphonuclear cells (PMN) in dogs were evaluated by flow cytometric analysis. Peripheral blood leukocytes (PBL) cultured with EWD showed the enhanced phagocytic response. The response was maximal when PBL were cultured with 100 - 400 micrograms/ml of EWD for 3 - 12 hr. Furthermore, significantly increased phagocytic responses were also induced even when PBL were cultured with protein components (200 micrograms/ml) of EWD such as conalbumin, flavoprotein and ficin-papain inhibitor for 3 hr. In addition, the enhancing effect of EWD on the phagocytic responses was also observed in MNC cultured with EWD (200 micrograms/ml) for 4 hr but not in PMN cultured with EWD in the same procedures. The supplement of the supernatant (20%) of MNC cultured with EWD (200 micrograms/ml) for 24 hr at 37 degrees C to PBL and MNC resulted in the enhancement of their phagocytic responses. In contrast, the supernatant of PMN cultured with EWD for 24 hr at 37 degrees C did not show any significant enhancing effect on the phagocytic responses of PBL, MNC and PMN. These results suggest that EWD has an enhancing effec...Continue Reading

Citations

Sep 23, 2014·Journal of the Science of Food and Agriculture·Sun Hee MoonHyun-Dong Paik
Nov 30, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ajay SrivastavaRamesh C Gupta
Dec 25, 2002·The Journal of Veterinary Medical Science·Moshira El-AbasyYoshikazu Hirota
Oct 16, 2002·Developmental and Comparative Immunology·Hang XieNarayan C Rath
May 25, 2005·Veterinary Immunology and Immunopathology·Mhan-Pyo YangEui-Bae Jeung

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