Enhancing the scope of in vitro maturation for fertility preservation: transvaginal retrieval of immature oocytes during endoscopic gynaecological procedures.

Human Reproduction
Xue-Ling SongJie Qiao

Abstract

Could in vitro maturation (IVM) following transvaginal oocyte retrieval during gynaecological surgery (IVM-surgery) be an effective and safe strategy for fertility preservation? IVM-surgery on unstimulated ovaries is a novel option that can be considered for fertility preservation for women requiring gynaecological surgery, but more research is needed to identify appropriate patients who may benefit and to determine the cost-effectiveness of such an approach. IVM followed by oocyte/embryo cryopreservation has been useful as a safe reproductive strategy for some infertile women. This prospective cohort study comprised 158 consecutive women with polycystic ovary syndrome (PCOS) who underwent laparoscopy or hysteroscopy for other reasons and had concomitant transvaginal oocyte retrieval followed by IVM between 2014 and 2016. A total of 158 women with anovulatory PCOS who underwent IVM-surgery in our infertility centre were recruited for this study. Matured IVM oocytes obtained from these women were either freshly fertilized and subsequently frozen at the blastocyst stage (fresh oocyte group, n = 46) or the oocytes were frozen (frozen oocyte group, n = 112) for fertility preservation followed by later thawing for insemination and c...Continue Reading

References

Dec 23, 2003·Human Reproduction·UNKNOWN Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
Apr 23, 2011·Reproductive Biomedicine Online·Hervé FernandezAmélie Gervaise
Dec 13, 2012·Future Oncology·Ana Luiza BerwangerMichael Grynberg
Feb 26, 2013·Fertility and Sterility·Rubens FadiniGiovanni Coticchio
May 12, 2016·Human Reproduction·Michael H DahanWeon-Young Son
Sep 25, 2016·Human Reproduction·Michel De VosRobert B Gilchrist
Nov 17, 2016·The Cochrane Database of Systematic Reviews·Jane ReaveyIngrid E Granne

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Citations

Jan 28, 2021·International Journal of Molecular Sciences·Irene PeinadoMaría José Gómez-Torres

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