PMID: 45569Jan 1, 1979

Enkephalin-dopamine interactions in behavioral arousal

Progress in Neuro-psychopharmacology
R J Katz, B J Carroll


1. Central injection of a long lasting enkephalin analog (D-Ala2-leu-enkephalin-amide) produced a syndrome of stereotyped motor activity. 2. This activation syndrome was significantly reduced by two dopamine (DA) blockers (pimozide, fluspririlene) and by an agonist of inhibition-mediating DA receptors [(3,4-dihydroxyphenylamino)-2-imidazoline]. 3. Intact DA functioning is necessary for the occurrence of this enkephalin-mediated behavioral syndrome.


Apr 1, 1987·Pharmacology, Biochemistry, and Behavior·D J CalcagnettiD L Margules
Jan 1, 1980·Peptides·G A OlsonD H Coy
Sep 1, 1980·The Journal of Pharmacy and Pharmacology·A J Goudie, C Demellweek


Aug 25, 1977·Nature·H PollardJ C Schwartz
Apr 1, 1978·Pharmacology, Biochemistry, and Behavior·R J KatzG Baldrighi
Sep 1, 1972·British Journal of Pharmacology·B J Carroll, P T Sharp
Jan 1, 1970·European Journal of Pharmacology·N E AndénU Ungerstedt

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Behavior, Animal
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Mental Disorders
Dopamine Receptor
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