PMID: 6365850Jan 1, 1984Paper

Enkephalin immunoreactivity in iris nerves: distribution in normal and grafted irides, persistence and enhanced fluorescence after denervations

Histochemistry
H BjörklundA Seiger

Abstract

The morphology and distribution of nerve fibers showing enkephalin-like immunoreactivity was studied in rat and mouse iris whole mounts. In adult rat, a relatively dense network of varicose fibers was seen throughout the iris. Individual, long, usually smooth fibers were observed running together with non-fluorescent fibers in bundles. Positive nerve fibers were also seen in the ciliary body and the choroid membrane. The fluorescence intensity was normally low. No enkephalin-positive fibers were detected in adult mouse iris. Extirpation or lesioning either one or all the three ganglia known to supply the rat iris with nerve fibers, the superior cervical, the ciliary and the trigeminal ganglia, caused no detectable decrease in amount of enkephalin-positive fibers. However, in irides grafted to the anterior eye chamber of adult recipients, no enkephalin-positive fibers could be observed 2-12 days postoperatively, strongly suggesting that degeneration of these fibers had occurred. When iris grafts were left longer in the eye, nerve fibers with enkephalin-like immunoreactivity reappeared. An increased fluorescence intensity was observed both in the ipsilateral and contralateral iris following extirpation or lesioning all three gang...Continue Reading

References

Nov 1, 1978·The Journal of Comparative Neurology·M SarP Cuatrecasas
Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·N BrechaC Laverack
Mar 1, 1976·Experimental Eye Research·A Huhtala
Oct 14, 1967·Nature·M StefaniniL Zamboni
Jun 1, 1966·Acta Physiologica Scandinavica·B Ehinger, B Falck
Jul 1, 1981·Experimental Eye Research·K TornqvistF Sundler
Jan 1, 1980·Neuroscience·M Del Fiacco, A C Cuello
Mar 1, 1980·Experimental Eye Research·J M ButlerW G Unger
May 29, 1981·Neuroscience Letters·A MillerI W Chubb
Jan 1, 1981·Peptides·J M Polak, S R Bloom
Mar 1, 1984·The Journal of Comparative Neurology·A SeigerH Björklund
Jun 1, 1981·The Journal of Comparative Neurology·J C FinleyP Petrusz

❮ Previous
Next ❯

Citations

Apr 1, 1986·Biulleten' eksperimental'noĭ biologii i meditsiny·I M KvetnoĭG M Deĭnenko
Jul 15, 1987·Experientia·R A StoneA M Laties
Jan 1, 1989·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·J LuthmanG Jonsson
Mar 22, 2008·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Shahid Husain, David E Potter
Jan 1, 1988·Clinical and Experimental Hypertension. Part A, Theory and Practice·T InagamiK Higashimori
Feb 1, 1987·Acta Ophthalmologica·T TervoA Vannas
Dec 1, 1985·Neuropeptides·D E HernandezS St-Pierre

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.