Enoxaparin-associated giant retroperitoneal hematoma in pulmonary embolism treatment.

North American Journal of Medical Sciences
Fahri Halit BesirLevent Kart

Abstract

Retroperitoneal hematoma may usually occur as a result of trauma. A life threatening retroperitoneal hematoma is not expected complication of anticoagulation treatment and rarely reported. Low molecular weight heparins (Enoxaparin) which are used as effective and safe medicine in the venous thromboemboly treatment have some major complications such as hematomas of different organs. We aim to present a giant spontaneous retroperitoneal hematoma after anticoagulant treatment of pulmonary embolism with enoxaparin. A 73-year-old male patient with the diagnosis of pulmonary embolism underwent anticoagulant treatment (enoxaparin). In the second day of admission, the patient had an episode of abdominal and back pain. Abdominal ultrasonography and computerized tomographic scan revealed a giant retroperitoneal hematoma. Enoxaparin treatment was then stopped and the supportive treatment was started. In the following days, hemoglobin levels returned to normal and a control CT revealed regression of hematoma size. The anticoagulant treatment with enoxaparin may lead to severe hematomas. Therefore, the clinical suspicion is required especially in elderly patients and patients with impaired renal function for retroperitoneal hematoma, when t...Continue Reading

Citations

Jun 29, 2014·The American Journal of Emergency Medicine·Nikolaos S SalemisStavros Gourgiotis
Nov 26, 2013·The Surgical Clinics of North America·George Kasotakis
Jan 25, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M Magro, I Gafson
May 23, 2015·AJR. American Journal of Roentgenology·Jennifer W UyedaAaron Sodickson

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