Enrollment of a population-based cohort of newborns at higher risk of developing a chronic condition: the EDEN study. Etude du Developpement des Nouveau-nés Study

International Journal of Epidemiology
V AddorA Calame

Abstract

To describe the methods used at birth to recruit a population-based cohort of newborns of all birthweights at higher risk of having a chronic condition, and to present baseline results. Screening of all newborns at hospital discharge for five non-exclusive criteria: (1) low birthweight (LBW), (2) congenital anomalies or genetic disease, (3) specified conditions associated with a high probability of chronicity, (4) referral to a neonatal intensive care unit (NICU), (5) or defined social problems. Calculation of Hobel risk scores for children satisfying > or = 1 criterion. All 6477 live births delivered in the 19 maternity hospitals of a geographically defined region (Vaud, Switzerland) to resident mothers in 1993-1994. Twelve per cent (n = 760) of newborns met > or = 1 criterion: 6.3% of all newborns had an LBW (criterion 1), 2.4% had a birth defect, 0.9% met criterion (3), 4.4% stayed in an NICU and 1.6% had serious social problems. Hobel prenatal score was high (> or = 10 points) for 41% of children with > or = 1 criterion, the intrapartum score for 87% and the neonatal score for 68%. Most newborns identified by the above simple criteria also had elevated perinatal risks. The validity of the criteria will later be tested again...Continue Reading

Citations

Mar 13, 1998·Fertility and Sterility·V AddorA Calame
Mar 15, 2008·European Journal of Pediatrics·Lidwine B MokkinkUNKNOWN Dutch National Consensus Committee Chronic Diseases and Health Conditions in Childhood
Oct 3, 2015·International Journal of Epidemiology·Kelly L MorganSinead T Brophy

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