Entanglement of sepsis, chronic kidney disease, and other comorbidities in patients who develop acute kidney injury

Seminars in Nephrology
Michael Heung, Jay L Koyner

Abstract

Acute kidney injury (AKI) is a common and severe complication for patients in the intensive care setting, often occurring in the setting of sepsis. Both sepsis and AKI are complex and heterogeneous syndromes with overlapping risk factors. Comorbidities - such as chronic kidney disease, diabetes mellitus, liver disease, cardiac disease and cancer - may contribute to the development of these syndromes and complicate their management. Recognition of the complex interplay between comorbid conditions, sepsis, and AKI is key to the successful management of these syndromes.

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Citations

Jul 15, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Kianoush KashaniDaryl J Kor
Feb 9, 2020·Scientific Reports·Myung-Gyu KimSang-Kyung Jo
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Dec 18, 2018·Frontiers in Medicine·Narayan Prasad, Manas Ranjan Patel
Jul 3, 2021·Antioxidants & Redox Signaling·Meagan S KingrenHiroshi Saito

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