PMID: 6413710Jul 1, 1983Paper

Enteral nutrition in malnourished patients with hepatic cirrhosis and acute encephalopathy

JPEN. Journal of Parenteral and Enteral Nutrition
P KeohaneD B Silk

Abstract

Ten patients with histologically proven cirrhosis, admitted in grade I to II acute hepatic coma, received in addition to a standard dietary protein free "anticoma" regime, a continuous nasogastric infusion of a branched-chain amino acid enriched chemically defined enteral diet (Hepaticaid) containing an equivalent of 70 g protein/day for a mean of 7.3 days (range 3-23). No complications of therapy were observed and, specifically, the use of fine bore tubes did not provoke variceal hemorrhage. Overall positive nitrogen balance (4.3 +/- 1.7 g N/day) was observed in patients fed 7 or more days. Improvement to coma grade 0 was seen in all patients save one, who died from hepatorenal failure. While serum ammonia levels remained elevated during the study period, there was a significant increase in the branched-chain/aromatic ratio (p less than 0.01) as plasma branched-chain amino acids rose (p less than 0.05) and tyrosine levels fell (p less than 0.05).

References

Jan 1, 1974·American Journal of Surgery·J E FischerF Deindoerfer
May 17, 1980·Lancet·B J JonesD B Silk
Oct 1, 1955·Journal of Consulting Psychology·R M REITAN

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Citations

May 18, 2013·Medizinische Klinik, Intensivmedizin und Notfallmedizin·M Plauth
Jul 1, 1986·The Proceedings of the Nutrition Society·D B Silk
Nov 13, 2003·Gut·M StroudUNKNOWN British Society of Gastroenterology
Jun 13, 2009·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Mathias PlauthUNKNOWN ESPEN
Sep 6, 2005·Gastroentérologie Clinique Et Biologique·Bernard CampilloPhuong Nhi Bories
May 13, 2008·Gastroenterology·Alastair O'Brien, Roger Williams
Nov 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·M L ChristieD Horst
May 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·L Marsano, C J McClain
Jun 27, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jeanette M Hasse, Sara R DiCecco
Apr 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C L MendenhallJ I Allen
Feb 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D J Nompleggi, H L Bonkovsky
Nov 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S SoberonC H Halsted
Apr 7, 2007·European Journal of Gastroenterology & Hepatology·Susannah R Green, Hamish D Duncan
Nov 14, 2001·Current Opinion in Clinical Nutrition and Metabolic Care·E Cabré, M A Gassull
Jan 22, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Xavier Hébuterne, Geoffroy Vanbiervliet
Jun 28, 2000·Current Opinion in Clinical Nutrition and Metabolic Care·S GopalanR Sengupta
Aug 28, 2003·Alimentary Pharmacology & Therapeutics·F StickelH K Seitz
Aug 31, 2015·GE Portuguese Journal of Gastroenterology·Marco SilvaGuilherme Macedo
Jan 1, 1985·Acta Medica Scandinavica. Supplementum·R D Johnson, R Williams
Sep 1, 1991·Gut·D B SilkC Wicks
Jan 1, 1997·Nutrition Reviews·C Corish
Nov 21, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Stephan C BischoffMathias Plauth

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