Enterococcus fecalis Sepsis and Leukemoid Reaction: An Unusual Association at Birth

Journal of Pediatric Hematology/oncology
Ashok KumarSriparna Basu

Abstract

Enterococcus fecalis is a nosocomial, opportunistic pathogen, known to cause late-onset sepsis in preterm neonates and is notorious for its association with high mortality and resistance to commonly used antibiotics, such as penicillin, ampicillin, aminoglycosides, and vancomycin. Neonatal leukemoid reaction, defined as the white blood cell count ≥50×10/L or absolute neutrophil count >30×10/L, is a poor prognostic factor in chorioamnionitis. Occurrence of neonatal leukemoid reaction in E. fecalis-mediated sepsis is rare. We report development of leukemoid reaction in a preterm, extremely low-birth-weight neonate with early-onset sepsis caused by E. fecalis that was resistant to ampicillin and aminoglycosides.

References

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Citations

Oct 6, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·N MoneyJ Blau
Jun 6, 2018·Frontiers in Microbiology·Diana Escuder-ViecoLeónides Fernández
Jan 6, 2021·International Journal of Molecular Sciences·Edith ReuschelMaria Emilia Solano

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Methods Mentioned

BETA
genetic exchange

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