Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin

Emerging Infectious Diseases
Iryna BukreyevaBenjamin Wyplosz

Abstract

Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.

References

Jun 21, 2002·The New England Journal of Medicine·Jean-Michel MolinaUNKNOWN Agence Nationale de Recherches sur le SIDA 090 Study Group
Aug 31, 2006·Current Opinion in Infectious Diseases·Elizabeth S Didier, Louis M Weiss
Sep 23, 2008·Transplant Infectious Disease : an Official Journal of the Transplantation Society·F LanternierO Lortholary
Jul 20, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L ChampionJ-M Molina
Mar 24, 2012·Journal of Clinical Microbiology·Christelle PomaresFlorent Morio
Dec 5, 2013·Transplant Infectious Disease : an Official Journal of the Transplantation Society·G DesoubeauxJ Chandenier

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Citations

Nov 1, 2020·The Journal of Antimicrobial Chemotherapy·Alexis MaillardJean-Michel Molina
Jun 8, 2021·Frontiers in Cellular and Infection Microbiology·Jialing BaoZeyang Zhou
Jul 1, 2021·Clinical Microbiology Reviews·Bing HanLouis M Weiss

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