PMID: 3767485Nov 1, 1986Paper

Enterogastric reflux and gastric clearance of refluxate in normal subjects and in patients with and without bile vomiting following peptic ulcer surgery

Annals of Surgery
C MackieA Cuschieri

Abstract

A noninvasive scintigraphic technique was used to estimate enterogastric reflux and subsequent gastric evacuation of refluxate in 35 normal, healthy subjects and 55 patients previously treated by vagotomy or partial gastrectomy. Reflux was provoked by a milk drink and quantitated by counting 99Tcm-EHIDA activity within the gastric area during gamma camera imaging. Seven normal subjects (20%) showed reflux of 5-18% of initial activity (mean: 10%), with peak values occurring at 5-30 minutes (mean: 14 minutes) following the milk. Gastric evacuation of activity in these subjects was monoexponential (r = 0.993, T1/2 = 24.1 minutes). Reflux occurred more frequently than normal in patients with truncal vagotomy and drainage (22/28 patients) and partial gastrectomy (20/21 patients). All of 16 patients with Billroth II anastomoses exhibited reflux, which was excessive compared with refluxing normal subjects (mean: 25%; p less than 0.01) and occurred later into the study (mean: 34 minutes; p less than 0.01). Ten of 11 asymptomatic patients showed reflux of similar amounts of activity (mean: 21%) compared with 16 patients who complained of bile vomiting (mean: 22%). However, asymptomatic patients exhibited gastric evacuation of refluxate ...Continue Reading

Citations

Mar 1, 1988·Digestive Diseases and Sciences·N J ParrC R Mackie
Feb 26, 2008·Lung·Ana Carla S AraujoElcio O Vianna
Sep 19, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·De-Chuan ChanYou-Chen Chao
Feb 5, 2004·Journal of the American College of Surgeons·Daniel T Dempsey
Feb 13, 2002·American Journal of Surgery·J ForsterR W McCallum
Dec 21, 2000·Alimentary Pharmacology & Therapeutics·P O Katz
Feb 13, 2008·BMC Gastroenterology·Sedef KuranBurhan Sahin
Dec 19, 2002·American Journal of Surgery·Anastasia StavrakaEvangelia Vlontzou
Sep 1, 1992·World Journal of Surgery·T H BrownK Ibrahim
Aug 26, 2011·Histopathology·Aoife Maguire, Kieran Sheahan
Feb 26, 2008·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·L Mello-FujitaL R A Bittencourt
Mar 25, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·G H KoekJ Tack
Feb 20, 2017·Obesity Surgery·Tuure SaarinenAnne Juuti

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