PMID: 6982027Sep 1, 1982Paper

Enteropathy complicating maintenance therapy in acute lymphoblastic leukaemia

Archives of Disease in Childhood
I J LewisJ Martin

Abstract

Seven patients being treated for acute lymphoblastic leukaemia between March 1976 and March 1981, in accordance with Medical Research Council protocols, developed clinical malabsorption while on maintenance chemotherapy. All of them received weekly methotrexate and 6 of the 7 were given co-trimoxazole. Five patients had folate deficiency. Stopping the anti-leukaemic therapy led to a resolution of gastrointestinal symptoms. A combined effect of methotrexate and co-trimoxazole is postulated.

References

Dec 10, 1977·British Medical Journal·A W CraftT J McElwain
Dec 29, 1977·The New England Journal of Medicine·W T HughesS L George
Jul 1, 1976·Archives of Disease in Childhood·S M ShaletD Pearson
Mar 11, 1972·British Medical Journal·I Chanarin, J M England
Apr 26, 1971·JAMA : the Journal of the American Medical Association·D Pinkel
Jan 17, 1981·Lancet·G M Baird, J F Dossetor

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Citations

Feb 1, 1988·European Journal of Pediatrics·J V PledgerE J Eastham
Sep 1, 1985·Archives of Disease in Childhood·C P SainsburyI A Hughes
Jun 1, 1987·Archives of Disease in Childhood·H P McDowellJ Martin
Mar 1, 1985·Journal of Clinical Pathology·D CunninghamR I Russell
Aug 23, 2006·Leukemia & Lymphoma·Aynur OğuzSeçil Ozkan
Dec 10, 2014·Clinical Lymphoma, Myeloma & Leukemia·Jitesh D Kawedia, Michael E Rytting
Jun 1, 1986·Archives of Disease in Childhood·D J Lloyd
Jan 1, 1989·Pediatric Hematology and Oncology·M S KibirigeM J Rennie

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