Abstract
During recent 20 years, enterovirus A71 (EV-A71) has emerged as a major concern among pediatric infectious diseases, particularly in the Asia-Pacific region. The clinical manifestations of EV-A71 include uncomplicated hand, foot, and mouth disease, herpanina or febrile illness and central nervous system (CNS) involvement such as aseptic meningitis, myoclonic jerk, polio-like syndrome, encephalitis, encephalomyelitis and cardiopulmonary failure due to severe rhombencephalitis. In follow-up studies of patients with EV-A 71 CNS infection, some still have hypoventilation and need tracheostomy with ventilator support, some have dysphagia and need nasogastric tube or gastrostomy feeding, some have limb weakness/astrophy, cerebellar dysfunction, neurodevelopmental delay, lower cognition, or attention deficiency hyperactivity disorder. Long term sequelae may be related to greater severity of CNS involvement or neuron damage, hypoxia and younger age of onset.
References
Mar 1, 1974·The Journal of Infectious Diseases·N J SchmidtH H Ho
Jan 1, 1982·Archives of Virology·G NagyI Dömök
May 1, 1993·The Pediatric Infectious Disease Journal·L J BaraffD L Schriger
May 18, 1999·Archives of Disease in Childhood·E LahatA Barzilai
May 26, 1999·Emerging Infectious Diseases·T N WuC Y Shen
Aug 5, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S M WangT F Yeh
Sep 25, 1999·The New England Journal of Medicine·M HoS R Shih
Sep 25, 1999·The New England Journal of Medicine·C C HuangT F Yeh
Nov 24, 1999·Lancet·L Y ChangC Y Lee
Oct 6, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L G ChanL J Anderson
Apr 9, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tzou-Yien LinMei-Hwan Wu
Jun 4, 2002·Pediatrics·Luan-Yin ChangTzou-Yien Lin
Mar 20, 2003·Emerging Infectious Diseases·Tzou-Yien LinChin-Yun Lee
Jan 15, 2004·JAMA : the Journal of the American Medical Association·Luan-Yin ChangTzou-Yien Lin
Apr 9, 2004·The Pediatric Infectious Disease Journal·Luan-Yin ChangTzou-Yien Lin
Nov 23, 2006·Pediatrics·Mei-Chih HuangChing-Chuan Liu
Mar 23, 2007·The New England Journal of Medicine·Luan-Yin ChangTzou-Yien Lin
Aug 3, 2007·Pediatrics·Kow-Tong ChenJyh-Yuan Yang
Nov 22, 2007·International Journal of Pediatric Otorhinolaryngology·Yung-An TsouJeng-Sheng Chang
Apr 29, 2008·Emerging Infectious Diseases·Tsuyoshi HamaguchiMasahito Yamada
Jul 9, 2008·Pediatrics·Susan Shur-Fen GauTzou-Yien Lin
Dec 6, 2008·Pediatrics and Neonatology·Luan-Yin Chang
Oct 22, 2010·The Lancet Infectious Diseases·Tom SolomonMong How Ooi
Oct 15, 2013·Pediatrics and Neonatology·Min-Yuan ChiaMin-Shi Lee
Jan 16, 2016·Vaccine·Ding-Ping LiuMing-Chin Yang
Citations
Sep 17, 2020·PLoS Pathogens·Kuan-Ying A HuangTzou-Yien Lin
Oct 3, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Sindy BöttcherUNKNOWN The Laboratory Network For Enterovirus Diagnostic LaNED
Nov 13, 2019·Journal of Biomedical Science·An-Ting LiouChiaho Shih
Feb 6, 2020·RNA Biology·Kuo-Ming LeeRei-Lin Kuo
Dec 29, 2020·Lancet·Olwen C MurphyUNKNOWN AFM working group
Feb 20, 2021·Journal of Medical Virology·Léa LucianiAntoine Nougairède
Mar 1, 2021·Vaccine·Michelle Hui Pheng LeeYoke Fun Chan
Mar 7, 2021·Vaccines·Mei-Ling LiGary Brewer
Mar 12, 2021·Emerging Microbes & Infections·Lu LiangHongjie Yu
Jun 26, 2020·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Jingjing LiMei Zeng
Jun 3, 2021·Pathogens·Chonnamet TechasaensiriBoonrat Tassaneetrithep
Jul 3, 2021·Journal of Neuroimmunology·Ronak K KapadiaAmanda L Piquet
Jul 18, 2020·Journal of Proteome Research·Zeyu SunDongli Pan
Jan 9, 2021·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Spencer C BarrettAndrew G Lee
Aug 24, 2021·Emerging Infectious Diseases·Everlyn KamauHeli Harvala
Aug 28, 2021·Cells·Maximilian HirschenbergerKonstantin Maria Johannes Sparrer
Jul 15, 2021·The Pediatric Infectious Disease Journal·Carol StephensSusana Felsenstein
Sep 17, 2021·ACS Infectious Diseases·Kristina LankoJohan Neyts
Nov 3, 2021·The Journal of Experimental Medicine·Jie ChenShen-Ying Zhang
Feb 23, 2020·Methods : a Companion to Methods in Enzymology·Mei-Ling Li, Gary Brewer
Nov 6, 2021·Voprosy virusologii·D V NovikovV V Novikov