Entomological investigation of Japanese encephalitis outbreak in Malkangiri district of Odisha state, India

Memórias do Instituto Oswaldo Cruz
Sudhansu Sekhar SahuPurushothaman Jambulingam

Abstract

A severe outbreak of Japanese encephalitis (JE) and acute encephalitis syndrome (AES) with high case fatality was reported from Malkangiri district of Odisha state, India during September to November 2016 affecting 336 children with 103 deaths. The purpose of this study was to investigate the outbreak in the light of entomological determinants. Entomological investigation was carried out in 48 villages from four mostly affected Community Health Centres (CHCs) of Malkangiri district. Dusk collections of resting adults was done in villages from indoor and outdoor sites to record the density of mosquito species, including the known JE vectors, feeding behaviour, parity, dusk index and infection status with JE virus (JEV). The per man hour density and dusk index of JE vector species varied from 2.5 to 24.0 and 0.81 to 7.62, respectively in study villages. A total of 1136 mosquitoes belonging to six vector species were subjected to PCR and one pool of Culex vishnui was found to be positive for JEV. The JE transmission in Malkangiri district was confirmed. Thorough screening of human blood samples of JE/AES suspected cases and JE vector mosquitoes for the presence of JEV during rainy season every year is recommended.

References

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Citations

Jul 24, 2020·The American Journal of Tropical Medicine and Hygiene·Grace YapLee Ching Ng
Jan 7, 2020·Pathogens and Global Health·Sudhansu Sekhar SahuJambulingam Purushothaman
Oct 31, 2020·The American Journal of Tropical Medicine and Hygiene·Zhidong LiuPeng Bi
Feb 20, 2021·Virus Research·Debajit DeyS Saif Hasan
Jul 3, 2021·Viruses·Heidi AuerswaldSebastien Boyer
Jul 3, 2021·Mathematical Biosciences and Engineering : MBE·Mondal Hasan Zahid, Christopher M Kribs

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Methods Mentioned

BETA
ELISA
dissection
PCR

Software Mentioned

Excel
SPSS

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