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Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model

Scientific Reports

Feb 17, 2017

Chiara CriscuoloNicola Origlia

Abstract

The Entorhinal cortex (EC) has been implicated in the early stages of Alzheimer's disease (AD). In particular, spreading of neuronal dysfunction within the EC-Hippocampal network has been suggested. We have investigated the time course of EC dysfunction in the AD mouse model carrying hu...read more

Mentioned in this Paper

Familial Alzheimer Disease (FAD)
Behavior, Animal
Adrenal Cortex Diseases
APP protein, human
Amyloid Beta Precursor Protein Measurement
Long Term Depression
Environment
Nerve Degeneration
Synaptic Transmission
Alzheimer's Disease
3
1
47
Paper Details
References
  • References10
  • Citations3
1

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Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model

Scientific Reports

Feb 17, 2017

Chiara CriscuoloNicola Origlia

PMID: 28205565

DOI: 10.1038/srep42370

Abstract

The Entorhinal cortex (EC) has been implicated in the early stages of Alzheimer's disease (AD). In particular, spreading of neuronal dysfunction within the EC-Hippocampal network has been suggested. We have investigated the time course of EC dysfunction in the AD mouse model carrying hu...read more

Mentioned in this Paper

Familial Alzheimer Disease (FAD)
Behavior, Animal
Adrenal Cortex Diseases
APP protein, human
Amyloid Beta Precursor Protein Measurement
Long Term Depression
Environment
Nerve Degeneration
Synaptic Transmission
Alzheimer's Disease
3
1
47

Similar Papers Found In These Feeds

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Paper Details
References
  • References10
  • Citations3
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