Entrapped paradoxical thromboembolism

Forensic Science, Medicine, and Pathology
Roger W Byard

Abstract

A 67-year-old obese woman (BMI 38.3) was found at autopsy to have deep venous thrombosis of the left calf with bilateral peripheral and saddle pulmonary thromboemboli and a 165 mm long segment of paradoxical thromboembolus wedged between the right and left atria through a patent foramen ovale. Death was due to acute right-sided decompensation caused by obstruction of the pulmonary outflow tract from bilateral pulmonary thromboemboli. Paradoxical thromboemboli pass from the venous system into the systemic circulation through intracardiac or intrapulmonary shunts causing ischemic injury to the brain, heart, intestines, kidneys and limbs. Very rarely, as in this case, they may become entrapped in a patent foramen ovale. Due to its entrapment the paradoxical embolism did not play a role in the lethal episode.

References

Mar 26, 2004·Current Problems in Cardiology·David R HolmesGuy S Reeder
Nov 3, 2009·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Pradeep RangappaPeter D Thomas
Apr 5, 2012·Journal of Forensic Sciences·Hannah E RosenfeldRoger W Byard
Dec 12, 2012·Journal of Forensic and Legal Medicine·Roger W Byard
Jul 26, 2014·Journal of the American College of Cardiology·Stephan WindeckerBernhard Meier
Aug 28, 2016·The American Journal of Medicine·Fateh Ali Tipoo SultanFarouk Mookadam
Jul 16, 2017·Trends in Cardiovascular Medicine·Koki NakanishiShunichi Homma
Jan 20, 2018·JACC. Cardiovascular Interventions·Claire E RaphaelDavid R Holmes
Mar 1, 2018·Forensic Science, Medicine, and Pathology·Danica CvetkovićSlobodan Nikolić
Mar 3, 2018·Journal of the American College of Cardiology·Mohammad K MojadidiBernhard Meier
Apr 10, 2018·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ryan CappaAndrew M Southerland
Apr 24, 2018·Journal of Neurology·Bruno MirandaJosé M Ferro

❮ Previous
Next ❯

Citations

Dec 29, 2020·Seminars in Thrombosis and Hemostasis·Nina D AnfinogenovaWladimir Y Ussov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.