Entropically induced asymmetric passage times of charged tracers across corrugated channels

The Journal of Chemical Physics
Paolo MalgarettiJ Miguel Rubi

Abstract

We analyze the diffusion of charged and neutral tracers suspended in an electrolyte embedded in a channel of varying cross section. Making use of systematic approximations, the diffusion equation governing the motion of tracers is mapped into an effective 1D equation describing the dynamics along the longitudinal axis of the channel where its varying-section is encoded as an effective entropic potential. This simplified approach allows us to characterize tracer diffusion under generic confinement by measuring their mean first passage time (MFPT). In particular, we show that the interplay between geometrical confinement and electrostatic interactions strongly affect the MFTP of tracers across corrugated channels hence leading to alternative means to control tracers translocation across charged pores. Finally, our results show that the MFPTs of a charged tracer in opposite directions along an asymmetric channel may differ We expect our results to be relevant for biological as well synthetic devices whose dynamics is controlled by the detection of diluted tracers.

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Citations

Jan 11, 2017·Physical Chemistry Chemical Physics : PCCP·Denis S Grebenkov, Gleb Oshanin
Aug 18, 2020·Physical Chemistry Chemical Physics : PCCP·A ValovG Oshanin
Sep 1, 2019·The Journal of Chemical Physics·Paolo MalgarettiJ Miguel Rubi
Mar 24, 2018·The Journal of Chemical Physics·Agata Wawrzkiewicz-Jałowiecka, Zbigniew J Grzywna
May 10, 2017·The Journal of Chemical Physics·Paolo Malgaretti, Holger Stark
Mar 20, 2018·Physical Review. E·Paolo Malgaretti, Markus Bier
Oct 4, 2018·The Journal of Chemical Physics·M MangeatD S Dean
Jun 24, 2020·The Journal of Chemical Physics·M MangeatD S Dean
Nov 10, 2018·The Journal of Chemical Physics·Antonio M PuertasIgnacio Pagonabarraga
Jan 22, 2021·Soft Matter·Paolo Malgaretti, Jens Harting

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