PMID: 44812Jan 1, 1979

Environmental chemical-induced modification of cell-mediated immune responses

Advances in Experimental Medicine and Biology
J B Silkworth, L D Loose

Abstract

It is therefore proposed that: 1) environmental chemicals can have specific mechanisms of toxicity and can influence antibody-mediated immunity while having no detectable effect on cell-mediated immunity, 2) immune dysfunction is related to exposure time to a chemical and the tissue concentration of that chemical, 3) recovery of immune function may occur even though chemical exposure continues, and 4) a single assay of immune function may not be appropriate to detect chemical induced immune dysfunction.

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