PMID: 3921424Mar 1, 1985Paper

Environmental control of prolactin synthesis in the teleost fish Oreochromis (formerly Sarotherodon) mossambicus

General and Comparative Endocrinology
S E Wendelaar BongaG J Van Eys


In the cichlid fish Oreochromis mossambicus prolactin cell activity is inversely related to the osmolarity and the Ca2+ concentration of the ambient water. Prolactin cell activity was estimated, at the end of a 3-week experimental period, by determination of the rate of prolactin synthesis during incubation of the rostral parts of the pituitary gland, in the presence of [3H]lysine. Since the secretory activity of isolated prolactin cells is known to be inversely related to the osmolarity of the incubation medium, the possibility was investigated that the effects of changes in ionic composition of the ambient water on prolactin secretion in vivo are mediated by changes in osmolarity of the blood plasma. No support was found for this hypothesis. In fish exposed to high water osmolarities prolactin cell activity was reduced, while plasma osmolarity increased. In contrast, at high Ca2+ concentrations of the water, when prolactin secretion was inhibited to a similar extent, plasma osmolarity was significantly reduced. Although direct effects of plasma osmolarity on prolactin cells cannot be excluded completely, it is unlikely that plasma osmolarity is the predominant factor in the control of prolactin cell activity in situ. The phys...Continue Reading


Jan 1, 1977·General and Comparative Endocrinology·S W FarmerC H Li
Jan 1, 1977·Endocrine Research Communications·J A Mattheij
Jun 1, 1968·General and Comparative Endocrinology·M Dharmamba, R Nishioka
Feb 1, 1968·General and Comparative Endocrinology·M Sage
Jun 1, 1981·General and Comparative Endocrinology·J N Ball
Aug 1, 1984·General and Comparative Endocrinology·S E Wendelaar BongaG Flik
Jan 1, 1980·Cell and Tissue Research·M OlivereauJ Olivereau


May 1, 1992·Fish Physiology and Biochemistry·N Mayer-Gostan, R Naon
Nov 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J L SpeckerH A Bern
Oct 1, 1988·General and Comparative Endocrinology·S E Wendelaar BongaG Flik
Aug 1, 1990·General and Comparative Endocrinology·L R Johnston, T Wigham
Jul 9, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Janet GenzW Gary Anderson

Related Concepts

High Pressure Liquid Chromatography Procedure
Lysine Hydrochloride
Pituitary Stalk

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.