Environmental exposure to non-persistent endocrine disrupting chemicals and semen quality: An overview of the current epidemiological evidence

International Journal of Occupational Medicine and Environmental Health
Dorota ZamkowskaMichał Radwan

Abstract

Some of the recent publications have reported a decline in semen quality in the last few decades. This phenomenon is associated with environmental factors, particularly with exposure to endocrine disrupting chemicals (EDCs). The aim of this publication is to critically review the literature on exposure to the following 6 ubiquitous environmental non-persistent EDCs: bisphenol A, triclosan, parabens, synthetic pyrethroids, organophosphate pesticides and phthalates, and on their influence on semen quality measured as sperm concentration, sperm volume, total sperm count, motility, total motile count, morphology, sperm motion, sperm DNA damage (comet extent, tail length, tail distributed moment, percent of DNA located in the tail (tail%), DNA fragmentation index, high DNA stainability, X:Y ratio and aneuploidy. Several electronic databases were systematically searched until 31 August 2016. Studies were qualified for the review if they: linked environmental exposure to non-persistent EDCs to semen quality outcomes, were published in English after 2006 (and, in the case of phthalates, if they were published after 2009) and were conducted in the case of humans. Out of the 970 references, 45 articles were included in the review. This r...Continue Reading

Citations

Jun 20, 2020·Andrologia·Manesh Kumar Panner SelvamRalf Henkel
Aug 9, 2020·Clinical Epidemiology·Katia Keglberg HærvigSandra Søgaard Tøttenborg
Aug 28, 2020·Toxics·Kajsa Ugelvig PetersenSandra Søgaard Tøttenborg
Jan 23, 2021·International Journal of Molecular Sciences·Antonietta SantoroRosaria Meccariello
Mar 7, 2021·International Journal of Environmental Research and Public Health·Thea Emily BensonGunnar Toft
May 19, 2021·Environmental Research·Jonathan Kiwitt-CárdenasAlberto M Torres-Cantero

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