Environmental exposures and family history of asthma

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
Shahid I SheikhDon Hayes

Abstract

Asthma pathogenesis is a complex interaction of genetic, ethnic, environmental and social/life style risk factors. The goal of this study was to identify associations, if any, in children with asthma, between environmental risk factors (exposure to second-hand tobacco smoke (STS), pet ownership, race and a family history of asthma. After IRB approval, from June 2011 to December 2014, 823 children with asthma were enrolled in this prospective cross sectional study. At the initial visit, families completed a questionnaire with information on family history of asthma, having a pet at home and exposure to STS by parents at home. Chi square analyses were calculated, with alpha level of significance ≤0.05. History of asthma in parents, siblings or grandparents was reported by 575 (69.8%) patients including father (n = 154, 17.8%) and mother (n = 235, 26.5%). Children with family history of asthma (n = 575) were significantly more likely to have a pet at home and exposure to STS (n = 347, 60.3% and n = 198, 34.4%, respectively) compared to families without a history of asthma (n = 124, 50%, p = 0.006 and n = 44, 17.7%, p < 0.001, respectively). Similarly, asthmatic children with exposure to STS (n = 241) were significantly more likely...Continue Reading

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Citations

Nov 12, 2016·International Journal of Environmental Research and Public Health·Alesia Ferguson, Helena Solo-Gabriele
Mar 10, 2017·International Journal of Environmental Research and Public Health·Alesia FergusonHelena Solo-Gabriele
Dec 13, 2019·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Vincent OjwangSuvi M Virtanen
Sep 25, 2019·European Journal of Public Health·Maya Leventer-RobertsRan Balicer
Aug 22, 2018·Current Allergy and Asthma Reports·Paivi M SaloDarryl C Zeldin

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