Environmental factors and the geoepidemiology of juvenile idiopathic arthritis

Autoimmunity Reviews
Yackov Berkun, Shai Padeh

Abstract

Juvenile idiopathic arthritis (JIA), the most common chronic rheumatic disease of childhood, is a clinically heterogeneous group of disorders characterized by chronic inflammatory arthritis. JIA is considered to be an autoimmune disease, which is a result of immune reaction caused or triggered by environmental factors such as infectious agents in a genetically susceptible host. The prevalence of JIA subtypes and different disease manifestations varies geographically. Various infectious agents have been suggested to be a trigger of JIA development. Numerous other factors, such as stressful life events and psychosociologic milieu, meteorological influence and maternal smoking, are suspected to be contributors of multicausal JIA pathogenesis. JIA is probably a basket of diseases rather than a single pathophysiological entity. Being a childhood autoimmune disease it could be viewed as an evolutional process or defect in the maturation of the immune system. Along the lines of the hygiene theory, multiple environment factors could interfere with the appearance and course of JIA, and no single causative factor could be been proven so far. Although many new data on the importance of the environment in JIA etiopathogenesis have appeared...Continue Reading

References

Mar 1, 1978·Arthritis and Rheumatism·M J HenochJ Baum
Jun 1, 1988·British Journal of Rheumatology·M H PritchardJ Munro
Feb 1, 1986·Arthritis and Rheumatism·J T CassidyJ G Schaller
Oct 31, 1985·The New England Journal of Medicine·J K ChantlerR E Petty
Sep 1, 1995·Annals of the Rheumatic Diseases·S WeinreichP Ivanyi
May 1, 1996·Indian Journal of Pediatrics·A Aggarwal, R N Misra
Nov 21, 2000·Rheumatic Diseases Clinics of North America·M HerrmannR H Straub
Jan 6, 2001·Arthritis and Rheumatism·P BaudoinB A Dijkmans
Aug 21, 2001·Rheumatology·O Kaipiainen-Seppänen, A Savolainen
Oct 15, 2003·Arthritis and Rheumatism·Sampath PrahaladJohn F Bohnsack
Aug 17, 2004·Annals of the Rheumatic Diseases·O KasapçopurN Arýsoy
Jan 11, 2005·Arthritis and Rheumatism·Rainer H StraubMaurizio Cutolo
Jun 21, 2005·Clinical Pediatrics·Frank T Saulsbury
Jul 26, 2005·Autoimmunity·Yackov BerkunYehuda Shoenfeld
Feb 1, 2007·Arthritis and Rheumatism·Evelien Zonneveld-HuijssoonNico M Wulffraat
Feb 8, 2007·Annals of the Rheumatic Diseases·Marloes W HeijstekNico M Wulffraat
May 29, 2007·Arthritis and Rheumatism·Judith Barash, Ofra Goldzweig
May 29, 2007·Arthritis and Rheumatism·R K SaurenmannE D Silverman
Sep 1, 2007·Arthritis Research & Therapy·Benedikt WeissbrichHermann J Girschick
May 21, 2008·Lupus·G Zandman-GoddardY Shoenfeld
Mar 26, 2009·Current Opinion in Rheumatology·Katherine P LiaoElizabeth W Karlson
Apr 11, 2009·The Journal of Infection·Syed Ahmed ZakiPreeti Shanbag
Jun 9, 2009·Pediatric Clinics of North America·Rebecca A Simmons
Sep 18, 2009·Annals of the New York Academy of Sciences·Gisele Zandman-GoddardYehuda Shoenfeld

❮ Previous
Next ❯

Citations

Sep 9, 2011·Journal of Clinical Immunology·Ninette AmariglioRaz Somech
Sep 3, 2010·Clinical Reviews in Allergy & Immunology·Guido Valesini, Fabrizio Conti
Jan 14, 2011·Clinical Reviews in Allergy & Immunology·Yinon ShapiraNancy Agmon Levin
Feb 22, 2011·Clinical Reviews in Allergy & Immunology·Daniel SmykDimitrios P Bogdanos
May 21, 2011·Clinical Reviews in Allergy & Immunology·Christopher Chang
Sep 3, 2011·Clinical Reviews in Allergy & Immunology·M Eric Gershwin, Yehuda Shoenfeld
Dec 29, 2011·Clinical Reviews in Allergy & Immunology·Yehuda Shoenfeld
Dec 22, 2011·Clinical Reviews in Allergy & Immunology·Wesley H Brooks
Mar 2, 2011·Cellular & Molecular Immunology·Nancy Agmon-LevinYehuda Shoenfeld
Jan 31, 2012·Genome Medicine·Corinne Richard-Miceli, Lindsey A Criswell
Jan 28, 2014·Journal of Autoimmunity·Eli M Eisenstein, Yackov Berkun
Nov 6, 2013·Case Reports in Rheumatology·Davide MorettiGabriele Simonini
Jul 28, 2012·Journal of Autoimmunity·Nancy Agmon-LevinYehuda Shoenfeld
Aug 7, 2012·Journal of Autoimmunity·Christophe JaminJacques-Olivier Pers
Mar 20, 2012·Best Practice & Research. Clinical Rheumatology·Nancy Agmon-Levin, Yehuda Shoenfeld
Mar 1, 2012·Journal of Autoimmunity·A G Tzioufas, P G Vlachoyiannopoulos
Sep 13, 2011·Journal of Autoimmunity·Andrea T BorchersM Eric Gershwin
Aug 2, 2011·AORN Journal·Anne Marie Herlehy
Jul 19, 2011·Autoimmunity Reviews·Chia-Chien Hsieh, Bi-Fong Lin
Jul 19, 2011·Autoimmunity Reviews·Sylvia C L FarhatAlfésio L F Braga
Jul 19, 2011·Autoimmunity Reviews·Carlo Selmi
Feb 16, 2011·Autoimmunity Reviews·Yu-Tsan LinBor-Luen Chiang
Sep 27, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Raivo UiboM Eric Gershwin
Nov 12, 2014·Clinical Reviews in Allergy & Immunology·Donato RiganteSusanna Esposito
Jan 10, 2012·Journal of Autoimmunity·Yehuda ShoenfeldM Eric Gershwin
May 5, 2011·JRSM Short Reports·Stephen J Genuis, Anna-Kristen J Siy
Feb 15, 2011·Cellular & Molecular Immunology·Raivo UiboM Eric Gershwin
May 16, 2018·Rheumatology International·Ewa GruszewskaBogdan Cylwik
May 31, 2019·Minerva medica·Marta PrioraEnrico Fusaro
Jan 1, 2011·Toxicological and Environmental Chemistry·Cynthia A Leifer, Rodney R Dietert
Jul 25, 2014·Annals of the Rheumatic Diseases·T H C M ReinardsM W Schilham

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

© 2022 Meta ULC. All rights reserved