Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas

Microbial Biotechnology
Huan LiJiapeng Qu

Abstract

Despite their important roles in host nutrition, metabolism and adaptability, the knowledge on how the mammalian gut microbial community assemble is relatively scanty, especially regarding the ecological mechanisms that govern microbiota along environmental gradients. To address this, we surveyed the diversity, function and ecological processes of gut microbiota in the wild plateau pika, Ochotona curzoniae, along the elevational gradient from 3106 to 4331 m on 'the Roof of the World'-Qinghai-Tibet Plateau. The results indicated that the alpha, beta and functional diversity of gut microbiota significantly increased with elevation, and elevation significantly explained the variations in the gut microbial communities, even after controlling for geographical distance, host sex and body weight. Some gene functions (e.g. nitrogen metabolism and protein kinases) associated with metabolism were enriched in the high-altitude pikas. Null model and phylogenetic analysis suggest that the relative contributions of environmental filtering responsible for local gut communities increased with elevation. In addition, deterministic processes dominated gut microbial communities in the high-altitude (more than 3694 m) pikas, while the percentages ...Continue Reading

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Citations

Nov 28, 2020·Journal of Applied Microbiology·Haijun LiaoYongping Kou
Feb 11, 2021·Microbial Biotechnology·Cheng WangMingliang Jin
Jun 25, 2021·Frontiers in Microbiology·Wenwen LiuHuayi Suo
Aug 10, 2021·Frontiers in Microbiology·Ni HanBi Yujing

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Datasets Mentioned

BETA
PRJEB26673

Methods Mentioned

BETA
environmental stress
PCR

Software Mentioned

PERMANOVA
metaxa2
PERMDISP
MRPP
flash
Uclust
vegan
PyNAST
R package
picante

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