Environmental Mycobacterium avium subsp. paratuberculosis Hosted by Free-Living Amoebae

Frontiers in Cellular and Infection Microbiology
Ascel Samba-LouakaYann Héchard

Abstract

Mycobacterium avium subsp. paratuberculosis is responsible for paratuberculosis in animals. This disease, leading to an inflammation of the gastrointestinal tract, has a high impact on animal health and an important economic burden. The environmental life cycle of M. avium subsp. paratuberculosis is poorly understood and several studies suggest that free-living amoebae (FLA) might be a potential environmental host. FLA are protozoa found in water and soil that are described as reservoirs of pathogenic and non-pathogenic bacteria in the environment. Indeed, bacteria able to survive within these amoebae would survive phagocytosis from immune cells. In this study, we assessed the in vitro interactions between several strains of M. avium subsp. paratuberculosis and Acanthamoeba castellanii. The results indicate that the bacteria were able to grow within the amoeba and that they can survive for several days within their host. To explore the presence of M. avium subsp. paratuberculosis in environmental amoebae, we sampled water from farms positive for paratuberculosis. A M. avium subsp. paratuberculosis strain was detected within an environmental amoeba identified as related to the poorly described Rosculus genus. The bacterial strai...Continue Reading

References

Jan 1, 1994·Critical Reviews in Microbiology·S Rodríguez-Zaragoza
Sep 1, 1997·Infection and Immunity·J D CirilloL E Bermudez
Jul 29, 1999·Preventive Veterinary Medicine·S L OttB A Wagner
Nov 27, 2002·Antonie van Leeuwenhoek·Klaus Jürgens, Carsten Matz
Apr 16, 2004·Clinical Microbiology Reviews·Gilbert Greub, Didier Raoult
Jan 11, 2005·Applied and Environmental Microbiology·Maëlle MolmeretYousef Abu Kwaik
Aug 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·Lingling LiVivek Kapur
Feb 4, 2006·Journal of Clinical Microbiology·Christine Y TurenneMarcel A Behr
Sep 14, 2007·Immunological Reviews·Kyle RohdeDavid G Russell
Nov 26, 2008·Journal of Bacteriology·David C AlexanderMarcel A Behr
Oct 23, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·I B SalahM Drancourt
Oct 31, 2012·Journal of Veterinary Internal Medicine·R W SweeneyA J Roussel
Jan 16, 2014·Microbiology·Ramzi GhodbaneMichel Drancourt
Feb 12, 2014·PloS One·Kenan HadziavdicChristofer Troedsson
Jul 16, 2014·Microbial Pathogenesis·M Drancourt
Sep 5, 2014·PLoS Neglected Tropical Diseases·Nana Ama AmissahMiriam Eddyani
Sep 24, 2014·Environmental Science & Technology·Vincent DelafontLaurent Moulin
Mar 17, 2015·Cellular Microbiology·Caroline BarischThierry Soldati

❮ Previous
Next ❯

Citations

Oct 7, 2020·Animals : an Open Access Journal From MDPI·Mary Garvey
Dec 29, 2020·Animal Health Research Reviews·Hyun-Eui Park, Han Sang Yoo
Nov 13, 2020·Frontiers in Microbiology·Israel RiveraEric T Harvill
Apr 14, 2020·Tuberculosis·Michelle H LarsenRichard T Robinson

❮ Previous
Next ❯

Datasets Mentioned

BETA
MG859939

Methods Mentioned

BETA
fluorescence microscopy
PCR
electrophoresis
genotyping

Software Mentioned

Map
BLASTn
GraphPad Prism

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved