Environmental Pollution by Benzene and PM10 and Clinical Manifestations of Systemic Sclerosis: A Correlation Study

International Journal of Environmental Research and Public Health
Alice BorghiniUmberto Moscato

Abstract

Atmospheric air pollution has been associated with a range of adverse health effects. The environment plays a causative role in the development of Systemic Sclerosis (SSc). The aim of the present study is to explore the association between particulate (PM10) and benzene (B) exposure in Italian patients with systemic sclerosis and their clinical characteristics of the disease. A correlation study was conducted by enrolling 88 patients who suffer from SSc at the Fondazione Policlinico "A. Gemelli" in Rome (Italy) in the period from January 2013 to January 2014. The average mean concentrations of B (in 11 monitoring sites) and PM10 (in 14 sites) were calculated using data from the Regional Environmental Protection Agency's monitoring stations located throughout the Lazio region (Italy) and then correlated with the clinical characteristics of the SSc patients. Of the study sample, 92.5% were female. The mean age was 55 ± 12.9 years old and the mean disease duration from the onset of Raynaud's phenomenon was 13.0 ± 9.4 years. The Spearman's correlation showed that concentrations of B correlate directly with the skin score (R = 0.3; p ≤ 0.05) and inversely with Diffusing Lung Carbon Monoxide (DLCO) results (R = -0.36; p = 0.04). This...Continue Reading

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Citations

Nov 28, 2019·International Journal of Environmental Research and Public Health·Xinpeng XingYue Zhu
Sep 30, 2020·Journal of Cutaneous Medicine and Surgery·Lydia OucheneElena Netchiporouk
Apr 13, 2020·Revue des maladies respiratoires·L SeséH Nunes
Sep 17, 2021·Dermatologic Therapy·Katerina DamevskaStefana Damevska

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